Lipid metabolism — Flashcards

What substrate accumulates in the lysosomes of a patient with Fabry disease? _____

Carnitine acyltransferase-1 (CPT-1) is regulated via negative feedback by _____

What substrate accumulates in the lysosomes of a patient with Niemann Pick disease? _____

Which three lipoproteins is apoprotein B-100 found on? _____

Which lipoprotein is formed by the degradation of VLDL and delivers TGs and cholesterol to the liver? _____

_____ -carbon steroids include both the mineralocorticoids and glucocorticoids (progesterone, deoxycorticosterone, aldosterone, and cortisol)

What is the precursor molecule to prostanoids and leukotrienes?_____

The first step of fatty acid synthesis is transport of _____ from the mitochondria to the cytosol through its shuttle

In the liver, acetoacetate may be converted to _____, which then travels to extrahepatic tissues (ketone body metabolism)

What substrate accumulates in the lysosomes of a patient with metachromatic leukodystrophy? _____