Lipid metabolism — Flashcards

Primary carnitine deficiency is characterized by muscle weakness and hypotonia, which is provoked by prolonged _____ (especially if fasting)

Which apolipoproteins (4) do chylomicrons express on their surface? _____

What is the effect of glucagon on blood fatty acid and ketoacid concentration?_____

Which three lipoproteins is apoprotein B-100 found on? _____

What is the precursor molecule to prostanoids and leukotrienes?_____

The first step of fatty acid synthesis is transport of _____ from the mitochondria to the cytosol through its shuttle

What substrate accumulates in the lysosomes of a patient with Niemann Pick disease? _____

In the liver, acetoacetate may be converted to _____, which then travels to extrahepatic tissues (ketone body metabolism)

What substrate accumulates in the lysosomes of a patient with metachromatic leukodystrophy? _____

7-hydroxylase is regulated via negative feedback by _____