Lipid metabolism — Flashcards

Vitamin B7 (biotin) is a cofactor for the enzyme _____ (fatty acid synthesis)

Which lysosomal storage disease is characterized by a cherry red spot on the macula and hepatosplenomegaly? _____

_____ deficiency is an inherited defect in the transport of long chain fatty acids into the mitochondria

_____ deficiency is characterized by an inability to break down medium-sized fatty acids

Bile acids, derived from _____, are released into the intestinal lumen

HMG-CoA may be converted to _____ via the enzyme HMG-CoA lyase (ketogenesis)

Which membrane-bound organelle is involved in the catabolism of very-long-chain fatty acids, branched-chain fatty acids, amino acids, and ethanol? _____

Which enzyme of the fatty acid synthesis pathway utilizes NADPH? _____

In the _____, the HMP shunt provides a source of NADPH for biosynthesis of fatty acids, cholesterol, and steroids

What substrate accumulates in the lysosomes of a patient with Fabry disease? _____