Lipid metabolism — Flashcards

Flashcard 131: Patients with homozygous familial hypercholesterolemia (very rare) have cholesterol levels of ~ _____ mg/dL

Answer: 700+

Flashcard 132: Which lipoprotein is secreted by intestinal epithelial cells and delivers dietary TGs to peripheral tissue? _____

Answer: Chylomicrons

Flashcard 133: _____ is an arachidonic acid pathway metabolite that causes neutrophil chemotaxis

Answer: LTB4

Flashcard 134: Are triglycerides polar or nonpolar? _____

Answer: Non-polar

Flashcard 135: In the blood, VLDLs pick up apoprotein _____ and _____ from circulating HDL

Answer: C-II

Flashcard 136: Can a urine test for ketones detect acetoacetate? _____

Answer: Yes

Extra: *DKA confirmed by measuring BHB in the SERUM

Flashcard 137: Which lipoprotein is formed by modification of IDL and delivers hepatic cholesterol to peripheral tissue? _____

Answer: LDL

Flashcard 138: Carnitine acyltransferase-1 (CPT-1) is regulated via negative feedback by _____

Answer: malonyl CoA

Flashcard 139: What substance is the precursor to bile acids, steroids, and vitamin D? _____

Answer: Cholesterol

Flashcard 140: What type of bond exists between fatty acids and glycerol (e.g. triglycerides)? _____

Answer: Ester bonds