Glycolysis — Flashcards

Flashcard 31: Pyruvate kinase is regulated via negative feedback by _____ and alanine

Answer: ATP

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Flashcard 32: What is the purpose of phosphorylating a sugar (e.g. glucose to glucose-6-phosphate)? _____

Answer: Prevent the sugar from leaving the cell

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Flashcard 33: _____ is converted to fructose-6-phosphate via the enzyme isomerase

Answer: Glucose-6-phosphate

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Flashcard 34: Von Gierke disease is characterized by very increased levels of _____ in the liver and kidneys, with subsequent hepatomegaly and renomegaly

Answer: glycogen

Flashcard 35: _____ is converted into pyruvate via the enzyme pyruvate kinase

Answer: Phosphoenolpyruvate

Flashcard 36: What substrate overrides inhibition of the enzyme phosphofructokinase-1 by ATP in the liver? _____

Answer: Fructose-2,6-bisphosphate

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Flashcard 37: Where in the cell does glycolysis occur? _____

Answer: Cytoplasm

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Flashcard 38: A(n) _____ enzyme catalyzes transfer of a phosphate group from a high-energy molecule (e.g. ATP) to a substrate

Answer: kinase

Flashcard 39: Conversion of phosphoenolpyruvate into pyruvate (glycolysis) produces a molecule of _____

Answer: ATP

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Flashcard 40: What glycolysis enzyme deficiency causes hemolytic anemia in a newborn? _____

Answer: Pyruvate kinase deficiency

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