Glycolysis US Medical PG Flashcards - Medical Study Cards
Master Glycolysis with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Glycolysis Flashcard Deck - 10 Cards
Flashcard 21: Once inside the pancreatic β-cell, glucose is _____ by the enzyme glucokinase
Answer: phosphorylated
Extra:
https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki
Flashcard 22: In skeletal muscle, glycogenolysis ultimately produces _____, which is rapidly metabolized during exercise
Answer: glucose-6-phosphate
Extra:
Watch Glycogen Synthesis (Glycogenesis) Degradation (Glycogenolysis) [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-glycogen-synthesis-glycogenesis-and-degradation-glycogenolysis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 23: Pyruvate kinase deficiency presents with _____ levels of 2,3-BPG
Answer: increased
Extra:
https://onlinemeded.org/spa/metabolism/glycolysis/acquire?ref=anki
Other:
Flashcard 24: Conversion of pyruvate into acetyl CoA releases a molecule of _____ and _____
Answer: CO2
Extra:
Watch Pyruvate Dehydrogenase Complex [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-pyruvate-dehydrogenase-complex?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Other:
Flashcard 25: In the **liver**, glycogen phosphorylase is **stimulated** by _____.
Answer: glucagon
Extra: Glucagon (liver) and epinephrine (liver and muscle) stimulate glycogen phosphorylase via a cAMP-mediated phosphorylation cascade.
Note: Glucagon does not act on skeletal muscle because muscle lacks glucagon receptors.
Flashcard 26: Fructose-1,6-bisphosphatase is allosterically stimulated by _____
Answer: citrate
Extra: Fructose-1,6-bisphosphatase is the rate-limiting enzyme of gluconeogenesis.
Regulation:
(+) Citrate
(-) AMP
(-) Fructose-2,6-bisphosphate
Note: Its regulation is the exact opposite of PFK-1.
Watch Gluconeogenesis: https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-gluconeogenesis
OnlineMedEd: https://onlinemeded.org/spa/metabolism/gluconeogenesis/acquire?ref=anki
Flashcard 27: Hexokinase is characterized by a(n) _____ Vmax relative to glucokinase
Answer: low
Extra:
Watch Glycogen Synthesis (Glycogenesis) Degradation (Glycogenolysis) [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-glycogen-synthesis-glycogenesis-and-degradation-glycogenolysis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/glycolysis/acquire?ref=anki
Other:
Flashcard 28: 3-phosphoglycerate is converted into _____ via the enzyme mutase
Answer: 2-phosphoglycerate
Extra:
Watch Glycolysis pt2 [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-glycolysis-part-2?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/glycolysis/acquire?ref=anki
Flashcard 29: Glucokinase is characterized by a(n) _____ Vmax relative to hexokinase
Answer: high
Extra:
Watch Glycogen Synthesis (Glycogenesis) Degradation (Glycogenolysis) [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-glycogen-synthesis-glycogenesis-and-degradation-glycogenolysis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki
Other:
Flashcard 30: Fructose-1,6-bisphosphate is converted into _____ and dihydroxyacetone-phosphate via the enzyme aldolase
Answer: glyceraldehyde-3-phosphate
Extra:
Watch Glycolysis pt1 [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-glycolysis-part-1?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/glycolysis/acquire?ref=anki
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