Drugs for Gastrointestinal Diseases — Flashcards

Loperamide is a _____ agonist that does not cross the BBB, therefore there is no analgesia and low potential for addiction

GI _____ is a PGE1 analog that may be used to prevent NSAID-induced peptic ulcers

Mesalamine (5ASA) works by inhibiting the synthesis of proinflammatory _____ and cytokines

Histamine, from ECL cells, activates _____ receptors (coupled to Gs) on the basolateral membrane of parietal cells

_____ is indicated with pyridoxine to reduce mild to moderate nausea and vomiting in the early stages of pregnancy

Polymerization of _____ occurs only at an acidic pH by crosslinking of the molecules, which helps in gastic ulcer protection

Cholestatic DrugsUrsodeoxycholic Acid is a synthetic secondary bile acid used primarily for patients with _____ gall stones that have contraindications to surgery

Ondansetron is used to treat _____ or post-operative induced nausea and vomiting

Sulfasalazine is metabolized by _____ into the active component (mesalamine) which is used to treat the colitis aspects of IBD

Metoclopramide has upper GI prokinetic effects, making it useful for treatment of _____ due to post-surgical disorders and diabetic gastroparesis