Drugs for Gastrointestinal Diseases — Flashcards

Guanylcycline C agonist indicated in _____ constipation is linaclotide.

Hint: acute/chronic

Histamine, from ECL cells, activates _____ receptors (coupled to Gs) on the basolateral membrane of parietal cells

GI_____ is a non-toxic bile acid used in the treatment of early primary biliary cirrhosis

GI _____ is a PGE1 analog that may be used to prevent NSAID-induced peptic ulcers

Ondansetron is used to treat _____ or post-operative induced nausea and vomiting

_____ is indicated with pyridoxine to reduce mild to moderate nausea and vomiting in the early stages of pregnancy

Sulfasalazine is metabolized by _____ into the active component (mesalamine) which is used to treat the colitis aspects of IBD

Polymerization of _____ occurs only at an acidic pH by crosslinking of the molecules, which helps in gastic ulcer protection

Cholestatic DrugsUrsodeoxycholic Acid is a synthetic secondary bile acid used primarily for patients with _____ gall stones that have contraindications to surgery

Metoclopramide has upper GI prokinetic effects, making it useful for treatment of _____ due to post-surgical disorders and diabetic gastroparesis