Drugs Affecting Blood and Blood Formation — Flashcards

Flashcard 71: Which r-tPA (fibrinolytic) has most affinity towards plasminogen bound to fibrin?_____

Answer: Tenecteplase

Flashcard 72: Ticagrelor, Cangrelor are _____ P2Y12 inhibitors

Answer: reversible (irreversible/reversible)

Flashcard 73: _____ is a monoclonal antibody directed against P-selectin, and reduces vaso-occlusive pain in sickle cell disease

Answer: Crizanlizumab

Flashcard 74: Most commercial preparations of heparin are extracted from _____ intestinal mucosa.

Answer: porcine (animal)

Flashcard 75: _____ is a competitive antagonist of _____ and inhibits thrombin-induced platelet aggregation.

Answer: Vorapaxar; PAR-1

Flashcard 76: IV _____ is an iron chelator indicated in patients with metabolic acidosis

Answer: deferoxamine

Flashcard 77: _____ has the least incidence of osteoporosis after prolonged use.

Answer: Fondaparinux::Anti-coagulant

Flashcard 78: Purple toe syndrome is an adverse effect of _____.

Answer: warfarin

Flashcard 79: Iron sucrose is a preparation of _____ iron.

Answer: Parenteral

Extra: Iron sucrose is a ferric (Fe3+) iron complex administered intravenously (parenterally). It is used when oral iron is not tolerated or ineffective.

Flashcard 80: _____ is a competitive antagonist of _____ and inhibits thrombin-induced platelet aggregation.

Answer: Vorapaxar; PAR-1