Plasma Expanders — Flashcards

Flashcard 1: Which fibrinolytic agent has the lowest incidence of intracranial hemorrhage?

Answer: Streptokinase

Extra: Streptokinase (a non-fibrin-specific thrombolytic) has a lower risk of intracranial hemorrhage (approx. 0.3%) compared to tPAs like Alteplase (approx. 0.7%). However, it is less effective at achieving TIMI 3 flow and is antigenic.

Flashcard 2: What are the routes of administration (2) of heparin? _____ (acute) or subcutaneous (prophylaxis)

Answer: IV

Flashcard 3: Which clotting factors are inactivated by the low molecular weight heparin (LMWH)? Mostly _____, but also Thrombin, Factor XIa, and Factor IXa

Answer: Factor Xa

Flashcard 4: Drug of choice in lithium induced polyuria is:

Answer: Amiloride

Flashcard 5: _____ is the anticoagulant of choice for patients requiring cardiopulmonary bypass.

Answer: Unfractionated heparin

Flashcard 6: _____ solutions are preferred over _____ for KCL administration for management of hypokalemia

Answer: Saline; Dextrose

Flashcard 7: _____, a synthetic metalloporphyrin is a potential alternative medical therapy for neonatal jaundice.

Answer: Sn-mesoporphyrin (SnMP)

Flashcard 8: _____ is considered superior to all other parenteral iron supplementation especially for postpartum IDA.

Answer: Ferric carboxymaltose

Flashcard 9: Treatment of hemophilia A involves _____ plus recombinant factor VIII

Answer: desmopressin

Flashcard 10: _____ is a competitive antagonist of PAR-1

Answer: Vorapaxar