Clinical Pharmacology and Drug Toxicity — Flashcards

The benzodiazepines that are safe to use in patients with liver disease may be remembered with the mnemonic "LOT": L: _____O: OxazepamT: Temazepam

_____ syndrome results from direct activation of mast cells leading to histamine release upon vancomycin administration

The higher incidence of allergic reaction due to _____ local anesthetics is because of the metabolite PABA

Hint: class

Which drugs are risk factors for transitional cell carcinoma? _____, Phenacetin

Conditions/agents for which **passive immunity** (pre-formed antibodies) is indicated in exposed, non-immune patients (Mnemonic: '**D**octor **T**o **B**e **H**ealed **V**ery **R**apidly'): - **D**: _____ - **T**: Tetanus - **B**: Botulism - **H**: HBV - **V**: Varicella - **R**: Rabies

Cystinuria may be treated with _____ agents, such as penicillamine

_____ is also used for the treatment of Oxalic acid and Hydrofluoric acid poisoning

Ribavirin is contraindicated in _____ due to its teratogenic effects

Ondansetron can prolong the _____ interval and induce torsades

Amphotericin related renal toxicity results in _____ due to decreased erythropoietin production