Clinical Pharmacology and Drug Toxicity — Flashcards

Tocilizumab is an anti-_____ monoclonal antibody indicated for Giant Cell Arteritis and Cytokine Release Syndrome

_____ works by inhibiting acetaldehyde dehydrogenase

Ondansetron can prolong the _____ interval and induce torsades

_____ and arsenic are particularly mutagenic carcinogens found in cigarette smoke

Hint: main

Cisplatin targets the _____ cells within the organ of corti, resulting in tinnitus and sensorineural hearing loss

_____ is a competitive antagonist of glycine at the postsynaptic receptors in the motor neurons of the anterior horn of the spinal cord.

Hint: Poison

_____ -dose Aspirin and Diuretics decrease uric acid secretion

Neuro/Psych _____ is an anti-epileptic associated with blood dyscrasias, such as aplastic anemia and agranulocytosis

Which HAART drugs are associated with peripheral neuropathy?_____

_____ syndrome results from direct activation of mast cells leading to histamine release upon vancomycin administration