Clinical Pharmacology and Drug Toxicity — Flashcards

Flashcard 381: _____ and doxazosin are drugs used in BPH that promote prostatic apoptosis

Answer: Terazosin

Flashcard 382: Among the **oral** forms of nicotine replacement therapy (NRT), nicotine _____ offer the highest level of nicotine delivery.

Answer: lozenges

Flashcard 383: _____ is recommended for reconstituting the BCG vaccine

Answer: Normal saline

Flashcard 384: Anaphylactoid reactions are _____ IgE mediated.

Answer: not

Flashcard 385: Raloxifene _____ the incidence of venous thrombosis

Answer: increases

Flashcard 386: Excess of _____ causes alkali disease in livestock.

Answer: selenium

Flashcard 387: _____ solutions are preferred over _____ for KCL administration for management of hypokalemia

Answer: Saline; Dextrose

Flashcard 388: The treatment of scurvy is the administration of vitamin C _____mg/day for _____ weeks.

Answer: 100-200; 12

Flashcard 389: _____ of the urine is useful in the management of amphetamine toxicity.

Answer: Acidification::Acidification/Alkalinisation

Flashcard 390: Drug of choice for ventricular premature beats (VPC) due to digitalis toxicity is:

Answer: Lidocaine (Lignocaine)

Extra: Management of Digitalis-induced arrhythmias: - **Lidocaine**: Drug of choice (DOC) for ventricular arrhythmias (e.g., VPCs, Ventricular Tachycardia). - **Phenytoin**: Traditionally considered DOC for digitalis-induced arrhythmias in general, especially supraventricular ones (e.g., Paroxysmal Atrial Tachycardia with AV block). - **Digoxin-specific antibody fragments (Digibind)**: The definitive antidote for life-threatening digitalis toxicity (e.g., severe hyperkalemia, hemodynamically unstable arrhythmias). - **Potassium**: Administered if hypokalemia is present, but contraindicated if AV block or hyperkalemia is present.