Clinical Pharmacology and Drug Toxicity Indian Medical PG Flashcards - Medical Study Cards
Master Clinical Pharmacology and Drug Toxicity with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Clinical Pharmacology and Drug Toxicity Flashcard Deck - 10 Cards
Flashcard 391: Drug of choice in intractable hiccups is:
Answer: Chlorpromazine
Extra: Chlorpromazine is the only FDA-approved drug for intractable hiccups and is traditionally considered the drug of choice in medical examinations.
Other medications used in management include:
- Baclofen (often preferred clinically due to fewer side effects)
- Gabapentin
- Metoclopramide
- Haloperidol
Flashcard 392: Drug of choice in Theophylline poisoning?
Answer: Activated Charcoal
Flashcard 393: Drug of choice for ventricular premature beats (VPC) due to digitalis toxicity is:
Answer: Lidocaine (Lignocaine)
Extra: Management of Digitalis-induced arrhythmias:
- **Lidocaine**: Drug of choice (DOC) for ventricular arrhythmias (e.g., VPCs, Ventricular Tachycardia).
- **Phenytoin**: Traditionally considered DOC for digitalis-induced arrhythmias in general, especially supraventricular ones (e.g., Paroxysmal Atrial Tachycardia with AV block).
- **Digoxin-specific antibody fragments (Digibind)**: The definitive antidote for life-threatening digitalis toxicity (e.g., severe hyperkalemia, hemodynamically unstable arrhythmias).
- **Potassium**: Administered if hypokalemia is present, but contraindicated if AV block or hyperkalemia is present.
Flashcard 394: The drug of choice for migraine in pregnancy is _______
Answer: Paracetamol
Flashcard 395: Drug of choice for ventricular premature beats(VPB) with digitalis toxicity is
Answer: Lidocaine
Flashcard 396: Drug of choice for malignant neuroleptic syndrome:
Answer: Dantrolene
Flashcard 397: The drug of choice for **early-onset (muscarinic)** mushroom poisoning is _______.
Answer: Atropine
Extra: Early-onset mushroom poisoning (e.g., *Inocybe*, *Clitocybe*) is characterized by muscarinic (SLUDGE) symptoms and is treated with **Atropine**.
Late-onset mushroom poisoning (e.g., *Amanita phalloides*) causes hepatotoxicity due to amatoxins. Management includes **multidose activated charcoal (MDAC)** to interrupt enterohepatic circulation, and specific agents like **Silibinin** (Silymarin) or Penicillin G.
Flashcard 398: Drug of choice for Epilepsy in pregnancy is -
Answer: Lamotrigine
Flashcard 399: Drug of choice in Acute central anticholinergic syndrome is -
Answer: Physostigmine
Flashcard 400: Drug of choice for myoclonic epilepsy in pregnancy is :
Answer: Levetiracetam
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