Clinical Pharmacology and Drug Toxicity — Flashcards

Cocaine can cause nasal mucosal _____ or septal perforation due to vasoconstriction

_____ deficiency causes increased risk of thrombotic skin necrosis with hemorrhage after warfarin administration

Chronic accumulation of _____ and pyrocatechol in carbolic acid poisoning leads to ochronosis

Drugs with a low therapeutic index may be remembered with the mnemonic 'Warning! These Drugs are Lethal': W: _____ T: Theophylline D: Digoxin L: Lithium

ACE inhibitors may precipitate _____ in bilateral renal artery stenosis, causing significantly increased serum creatinine

_____ is a PPAR gamma agonist has been withdrawn from many countries including India due to increased cardiovascular mortality.

Sulfasalazine is a combination of _____ (anti-inflammatory) and Sulfapyridine (anti-bacterial), and thus is contraindicated in patients with sulfa allergies

Can the MMR vaccine be given to pregnant patients? _____

Which antibiotics (2) can prolong the QT interval? _____

Absolute contraindications to OCPs include: - History of _____ or thromboembolism - History of an estrogen-dependent tumor - Women > 35 years who smoke heavily