Clinical Pharmacology and Drug Toxicity — Flashcards

Niacin can cause elevated _____ function tests with severe hepato-toxicity

Hydrolysis of fosphenytoin yields _____ which increases the risk of hyperphosphatemia in renal failure patients.

Niacin may cause _____ as an adverse effect, which can precipitate gout

In case of cyanide poisoning, there is _____ in the absence of hypoxemia (hypoxemia/hypoxia)

Adverse effects of epoprostenol and iloprost include _____ and jaw pain

Prednisolone is given at the daily dose of _____ mg/kg (max 60 mg) for 6 weeks, followed by an alternate day dose of 1.5 mg/kg (max 40 mg) for the next 6-8 weeks for Minimal Change Disease.

Which NNRTIs (2) are teratogenic? _____

In addition to typical opioid adverse effects, tramadol also may cause decreased _____ threshold and serotonin syndrome

High-dose Cladribine use can result in _____-toxicity and neuro-toxicity

Which antidiarrheal mu-opioid agonist has a higher potential for addiction? _____