Clinical Pharmacology and Drug Toxicity — Flashcards

Use of Griseofulvin is contraindicated in _____ and/or breast-feeding women

The inhaled anesthetic _____ can induce seizures and cause nephro-toxicity as adverse effects

Children with _____ encephalopathy should receive combined chelation therapy with Dimercaprol  and calcium disodium edetate (CaNa2EDTA).

The H2 receptor antagonist _____ has many anti-androgenic effects (e.g. gynecomastia, impotence, elevated prolactin levels)

Which antibiotics (2) can prolong the QT interval? _____

Cholestatic DrugsPatients using Obeticholic Acid commonly experience _____, but incorrect dosing can lead to serious liver injury

Adverse effects of gabapentin include _____ and ataxia

Nitroprusside is associated with _____ poisoning, which may present as - lactic acidosis- seizures- altered mental status

Niacin can cause elevated _____ function tests with severe hepato-toxicity

Sulfasalazine is a combination of _____ (anti-inflammatory) and Sulfapyridine (anti-bacterial), and thus is contraindicated in patients with sulfa allergies