Antimicrobial Agents — Flashcards

Flashcard 361: _____ is the drug of choice for human infections with Fasciola hepatica.

Answer: Triclabendazole

Flashcard 362: Oral terbinafine at 250 mg/day is given for a duration of _____ weeks for fingernails infection

Answer: 6

Flashcard 363: Artemesinin derivatives and Chloroquine are _____ onset acting schizonticides.

Answer: fast

Flashcard 364: Which fluoroquinolone is NOT approved for use in UTIs?_____

Answer: Moxifloxacin

Flashcard 365: Amphotericin B colloidal dispersion contains equimolar amounts of amphotericin B and _____.

Answer: cholesteryl sulfate

Flashcard 366: _____ is the drug of choice for coccidioidal meningitis

Answer: Fluconazole

Flashcard 367: All contacts of diphtheria should receive antibiotic prophylaxis _____, regardless of immunization status

Answer: (benzathine penicillin G or erythromycin)

Flashcard 368: According to the MOHFW 2020 guidelines, which drug is the preferred **third drug** for HIV Post-Exposure Prophylaxis (PEP)?

Answer: Dolutegravir (DTG)

Extra: The preferred 3-drug PEP regimen as per MOHFW 2020 guidelines is: **Tenofovir (TDF) + Lamivudine (3TC) + Dolutegravir (DTG)** for 28 days.

Flashcard 369: Which triple drug combination is used for mass prophylaxis and transmission interruption of filariasis?_____

Answer: Ivermectin, DEC and Albendazole

Flashcard 370: _____ is the drug of choice for toxoplasmosis in pregnancy to prevent vertical transmission

Answer: Spiramycin

Extra: Spiramycin is used for the prevention of vertical transmission of toxoplasmosis when maternal infection is suspected or confirmed (and the fetus is not yet infected). If fetal infection is confirmed or for the treatment of cerebral/disseminated toxoplasmosis, the drug of choice is **Pyrimethamine + Sulfadiazine + Folinic acid** (Leucovorin).