Antimicrobial Agents — Flashcards

The primary mode of resistance to fluoroquinolones is due to mutation in _____ or due to plasmid-mediated resistance

If a patient with CAP has received antibiotics in the past 3 months or if there is a high level of macrolide resistance in the region, a course of _____ or beta-lactam plus macrolide is given.

Which two anti-influenza drugs inhibit the M2 channels? _____

_____ is a drug that works by blocking Plasmodium heme polymerase (enzyme)

Which antibiotics bind divalent ions (Fe2+, Ca2+, and Mg2+) resulting in chelation?_____

_____ is an irreversible β-lactamase inhibitor that is combined with piperacillin (antipseudomonal penicillin) (Zosyn).

Second generation cephalosporins have _____ activity against gram-positive bacteria when compared with first generation cephalosporins.

_____ and Pneumocystis jirovecii are treated prophylactically in HIV patients with Trimethoprim-sulfamethoxazole (TMP-SMX)

CMV can gain resistance to ganciclovir via mutations in the _____ gene or its DNA polymerase

Treatment of Rabies virus includes administration of _____ and rabies immunoglobulin (passive immunization)