Neoplasia — Flashcards

Small cell carcinoma is characterized histologically by _____ differentiated small cells and is thus very aggressive

_____ carcinoma of the lung may secrete the hormone -hCG

Birt-Hogg-Dube syndrome is due to _____ mutation and presents with multiple oncocytomas, chromophobe RCCs, facial fibrofolliculomas, lung cysts and spontaneous pneumothorax

ER/PR-_____, HER2-negative cancers is the most common subtype of breast cancer in individuals who inherit germline mutations in BRCA1

2-Napthylamine is a carcinogenic aromatic amine found in _____ associated with Transitional Cell Carcinoma of the Bladder

_____ is a salivary gland tumor composed of chondromyxoid stroma and epithelium

-fetoprotein (AFP) is a serum tumor marker elevated in (mnemonic: HE-MAN is the alpha male)- H_____- Endodermal sinus (yolk sac) tumor- Mixed germ cell tumor- Ataxia-telangiectasia- Neural tube defects

Peutz-Jeghers-Touraine syndrome is due to loss-of-function mutation of _____ gene

IHC score is said to be 1+ if the breast cancer is HER2 _____

Her2 enriched subtype of breast cancer usually has a _____ Ki67