Hematopathology — Flashcards

Flashcard 151: Disorders of fibrinolysis typically present with _____ PT and increased PTT

Answer: increased

Flashcard 152: Burkitt lymphoma classically presents as an extranodal mass in a _____ or young adult (age group)

Answer: child

Flashcard 153: Hereditary _____ is diagnosed by the osmotic fragility test

Answer: spherocytosis

Flashcard 154: Ig_____-mediated immune hemolytic anemia usually causes extravascular hemolysis

Answer: G

Flashcard 155: In _____ deficiency, oxidative stress precipitates denaturated hemoglobin as Heinz bodies

Answer: G6PD

Flashcard 156: Lymphoma is divided into _____ (~85%) and Hodgkin lymphoma (~15%) *bonus: age groups

Answer: non-Hodgkin

Extra: Age groups: - Hodgkin Lymphoma: Bimodal distribution (peaks in young adults ~20s and elderly ~50s+). - Non-Hodgkin Lymphoma: Generally occurs in older adults (incidence increases with age).

Flashcard 157: The _____ Coombs test adds donor blood and anti-Ig antibody (Coombs reagent) to the patient's serum

Answer: indirect

Flashcard 158: When exposed to conditions that favor the _____ form of Hemoglobin, HbS polymerizes and forms needle-like structures ("sickle cells")

Answer: taut

Flashcard 159: Diffuse Large B-Cell Lymphoma is most commonly caused by alterations in _____ or Bcl-6

Answer: Bcl-2

Flashcard 160: _____ is a neoplastic proliferation of mature myeloid cells, especially megakaryocytes

Answer: Myelofibrosis