Endocrine Pathology Indian Medical PG Flashcards - Medical Study Cards
Master Endocrine Pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Endocrine Pathology Flashcard Deck - 49 Cards
Flashcard 1: What type of thyroid carcinoma is illustrated in this histology slide?
_____
Answer: medullary carcinoma
Flashcard 2: What type of thyroid carcinoma is illustrated in this histology slide?
_____
Answer: anaplastic carcinoma
Flashcard 3: _____ colloid is a characteristic histological finding associated with Graves disease
Answer: Scalloped
Flashcard 4: In Riedel thyroiditis, fibrosis may extend to _____, thus mimicking anaplastic carcinoma
Answer: local structures (e.g. airway)
Flashcard 5: _____ calcification in the form of psammoma bodies is seen in Papillary thyroid carcinoma.
Answer: Dystrophic
Flashcard 6: Hurthle cell carcinoma is a variant of _____ thyroid carcinoma consisting of oxyphil (Hurthle, Askanazy) cells containing abundant mitochondria
Answer: follicular
Flashcard 7: Thyroid _____ carcinoma is a malignant proliferation of parafollicular "C" cells
Answer: medullary
Flashcard 8: Thyroid _____ carcinoma may be lined by cells with clear, 'Orphan Annie eye' nuclei
Answer: papillary
Flashcard 9: Crooke hyaline change is a characteristic feature of _____ and adrenal glands, seen in Cushing syndrome
Answer: pituitary
Flashcard 10: Which two antibodies are associated with Hashimoto thyroiditis? _____ and anti-thyroid peroxidase (anti-microsomal)
Answer: Anti-thyroglobulin
Flashcard 11: Hashimoto thyroiditis is associated with HLA-_____ and HLA-DR5
Answer: DR3
Flashcard 12: A _____ pattern of chromaffin nests is diagnostic for paraganglioma or pheochromocytoma
Answer: zellballen
Flashcard 13: On histology, patients with postpartum thyroiditis exhibit a _____ infiltrate with occasional germinal center formation
Answer: lymphocytic
Flashcard 14: _____ is the most common tumor of the adrenal medulla in adults
Answer: Pheochromocytoma
Flashcard 15: Waterhouse-Friderichsen syndrome is the bilateral _____ necrosis of the adrenal glands, causing the gland to look like a "sack of blood"
Answer: hemorrhagic
Flashcard 16: Papillary thyroid microcarcinomas (PTMs) are defined as PTCs with a maximum diameter of d_____mm and non-palpable
Answer: 10
Flashcard 17: In thyroid medullary carcinoma, calcitonin often deposits within the tumor as _____, which may be visualized with a congo red stain
Answer: amyloid
Flashcard 18: Thyroid _____ carcinoma may have psammoma bodies on biopsy, which are characterized by concentric layers of calcification
Answer: papillary
Flashcard 19: Which criteria should be met to classify a differentiated thyroid cancer as low risk?< _____ years (better prognosis)Unifocal lesionSize < 2 cmNo lymphovascular invasionNo capsular invasion
Answer: 40
Flashcard 20: Exposure to _____ in childhood is a major risk factor for thyroid papillary carcinoma
Answer: ionizing radiation
Flashcard 21: Thyroid follicular carcinoma is characterized by a malignant proliferation of follicles surrounded by a _____ with invasion through the capsule
Answer: fibrous capsule
Flashcard 22: Type 1 diabetes mellitus is due to _____ of pancreatic beta cells by anti-glutamic acid decarboxylase antibodies
Answer: autoimmune destruction
Flashcard 23: Mutations of the pituitary-specific gene _____ can lead to the development of a somatotroph adenoma
Answer: PIT-1
Flashcard 24: Calcitonin and serotonins are responsible for _____ in Medullary thyroid cancer
Answer: diarrhea
Flashcard 25: Defect in thyroid hormone transport gene _____ can lead to primary hypothyroidism
Answer: MCT8
Flashcard 26: The _____ variant of papillary thyroid cancer is characterised by diffuse fibrosis throughout the gland with absent BRAF mutations
Answer: diffuse sclerosing
Flashcard 27: Pituitary tumors showing pleomorphism and atypical mitosis are termed _____
Answer: atypical adenomas
Flashcard 28: Depletion of cortical cell _____ is seen in adrenal gland in shock
Answer: lipids
Flashcard 29: Can FNAC be used in Reidel's thyroiditis?_____
Answer: No
Flashcard 30: _____ thyroid carcinoma is the most common thyroid malignancy in iodine-sufficient areas
Answer: Papillary
Flashcard 31: Lateral aberrant thyroid almost always represents metastatic thyroid cancer in _____
Answer: lymph nodes.
Flashcard 32: Which is the key diagnostic technique while evaluating thyroid nodules?_____
Answer: FNA biopsy
Flashcard 33: Which is a carcinoma of the follicular epithelium of thyroid?_____
Answer: Follicular, Papillary and Anaplastic
Flashcard 34: Risk of malignancy in solid thyroid swellings is _____ than cystic swellings
Answer: more
Flashcard 35: Presence of _____ is an absolutely necessary criterion for the diagnosis of pituitary carcinoma
Answer: craniospinal metastasis
Flashcard 36: Which fixative is used for adrenal biopsy?_____
Answer: Orth's fluid
Flashcard 37: Microcarcinoma or occult carcinoma refers to _____ thyroid carcinoma.
Answer: small papillary
Flashcard 38: The _____ variant of papillary thyroid cancer is associated with chernobyl nuclear accident
Answer: solid
Flashcard 39: Sustentacular cells of paragangliomas stain positive for _____
Answer: S-100
Flashcard 40: The _____ variant of papillary thyroid cancer has elongated nuclei with pseudostratification of the nuclei
Answer: columnar cell
Flashcard 41: Cells in insulinoma are _____morphic
Answer: mono
Flashcard 42: Liver metastasis is more common in _____ thyroid carcinoma.
Answer: medullary
Flashcard 43: The most common variant of papillary carcinoma thyroid is the _____ variant.
Answer: follicular
Flashcard 44: Patients with a history of untreated differentiated thyroid carcinoma (DTC), may develop _____ thyroid cancer
Answer: anaplastic
Flashcard 45: Hurthle cell carcinoma are _____ likely to metastasis compared to FTC
Answer: more
Flashcard 46: Deposition of _____ is a characteristic feature of an insulinoma
Answer: amyloid
Flashcard 47: Aldosterone-producing adenomas show the presence of eosinophilic, laminated cytoplasmic inclusions, known as _____ bodies
Answer: spironolactone
Flashcard 48: Most common cancer arising from a thyroglossal cyst is _____ carcinoma.
Answer: papillary
Flashcard 49: Papillary thyroid carcinoma metastasis to the ipsilateral neck nodes is also known as _____ thyroid.
Answer: lateral aberrant
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