Adrenal Cortical Disorders — Flashcards

Flashcard 1: Depletion of cortical cell _____ is seen in adrenal gland in shock

Answer: lipids

Flashcard 2: Aldosterone-producing adenomas show the presence of eosinophilic, laminated cytoplasmic inclusions, known as _____ bodies

Answer: spironolactone

Flashcard 3: Crooke hyaline change is a characteristic feature of the _____, seen in Cushing syndrome

Answer: pituitary gland

Extra: Crooke hyaline change occurs in the anterior pituitary corticotrophs in patients with Cushing syndrome (due to any cause). The normal granular cytoplasm is replaced by homogenous, pale, eosinophilic material consisting of keratin intermediate filaments, representing a response to high glucocorticoid levels.

Flashcard 4: What type of thyroid carcinoma is illustrated in this histology slide? _____

Answer: medullary carcinoma

Flashcard 5: What type of thyroid carcinoma is illustrated in this histology slide? _____

Answer: anaplastic carcinoma

Flashcard 6: _____ calcification in the form of psammoma bodies is seen in Papillary thyroid carcinoma.

Answer: Dystrophic

Flashcard 7: _____ colloid is a characteristic histological finding associated with Graves disease

Answer: Scalloped

Flashcard 8: Hurthle cell carcinoma is a variant of _____ thyroid carcinoma consisting of oxyphil (Hurthle, Askanazy) cells containing abundant mitochondria

Answer: follicular

Flashcard 9: In Riedel thyroiditis, fibrosis may extend to _____, thus mimicking anaplastic carcinoma

Answer: local structures (e.g. airway)

Flashcard 10: Which two antibodies are associated with Hashimoto thyroiditis? _____ and anti-thyroid peroxidase (anti-microsomal)

Answer: Anti-thyroglobulin