Immunology — Flashcards

Flashcard 61: Different types of immunodiffusions:_____ diffusion in one dimension - Oakley-Fulthorpe procedure

Answer: Double

Flashcard 62: _____ -cells can secrete capsular antibodies (IgG) against bacteria who secrete a capsule

Answer: B

Flashcard 63: Antigen loading onto MHC I occurs in the RER after breakdown of endogenous antigen by the _____ in the cytosol, and delivery to the RER via TAP (transporter associated with antigen processing)

Answer: proteasome

Flashcard 64: _____ and Interferon-β are glycoproteins synthesized by virus-infected cells that act locally on uninfected cells, "priming" them for viral defense

Answer: Interferon-α

Extra: Type I Interferons (IFN-α and IFN-β) act in a paracrine fashion to induce an antiviral state in neighboring cells by activating RNAse L (degrades viral mRNA) and Protein Kinase R (inhibits translation initiation).

Flashcard 65: Antigen-independent antibody diversity in _____ chains is generated by V(D)J gene recombination

Answer: heavy

Flashcard 66: _____ binds factor H and breaks down C3-convertase

Answer: M protein

Flashcard 67: Interferon-_____ is produced by leukocyte

Answer: alpha

Flashcard 68: MHC _____ binds to the T-cell receptor (TCR) and CD-4

Answer: II

Flashcard 69: The antigen receptors of T lymphocytes have one _____ and beta chain (monovalent)

Answer: alpha

Flashcard 70: _____ are exotoxins that cause a massive amount of T-cell activation

Answer: Superantigens