Tumor Immunology — Flashcards

Flashcard 1: Different types of immunodiffusions:_____ diffusion in two dimension - Radial immunodiffusion procedure

Answer: Single

Flashcard 2: Natural killer cells may kill cells via binding between _____ (NK cells) and the Fc region of IgG-bound antigen

Answer: CD16

Flashcard 3: Class _____ MHC encodes for tumour necrosis factor and complement proteins (C2, C4, Factor B).

Answer: III

Flashcard 4: Class switching to Ig_____ is promoted by IL-5 and TGF-β

Answer: A

Flashcard 5: Which type of TCR recognizes antigens without the requirement of MHC?

Answer: γδ (Gamma-delta) T cells

Extra: Most T cells are αβ T cells which require MHC-restricted antigen presentation. In contrast, γδ T cells (Gamma-delta T cells) can recognize antigens (including non-peptide antigens like lipids and phosphoantigens) directly without the requirement for MHC molecules.

Flashcard 6: _____ chemokines include monocyte chemoattractant protein (MCP1), eotaxin, macrophage inflammatory protein 1 (MIP1), and regulated and normal T-cell expressed and secreted (RANTES)

Answer: C-C

Flashcard 7: CD79a and CD79b are present on _____ cells essential for signal transduction through the antigen receptor.

Answer: B

Flashcard 8: MHC _____ binds to the T-cell receptor (TCR) and CD-8

Answer: I

Flashcard 9: Which interleukins stimulate proliferation of natural killer cells?_____

Answer: IL-2 and IL-15

Flashcard 10: father of immunology is

Answer: Edward Jenner louis pasteur is the father of bacteriology

Extra: