Major Histocompatibility Complex — Flashcards

Flashcard 1: MHC _____ presents endogenously synthesized antigens to CD8+ cytotoxic T cells

Answer: I

Flashcard 2: _____ Lymphoid Cell Function B & T cells - Found in bloodstream, lymph nodes, spleen, submucosa, and epithelia B cells: contain markers CD19, CD20, CD21 - Mature into plasma cells - Function is to produce antibodies TH cells: contain markers CD3 and CD4 - Function is to regulate immune responses Cytotoxic T cells: contain markers CD3 and CD8 - Function is to kill infected cells NK cells - Contain markers CD16 and CD56 - Function is to kill tumor/virus cell targets or antibody-coated target cells - T cells can only bind peptides that have been processed and presented by major histocompatibility complexes (MHCs)

Answer: Basic

Flashcard 3: CD79a and CD79b are present on _____ cells essential for signal transduction through the antigen receptor.

Answer: B

Flashcard 4: MHC _____ presents exogenously synthesized antigens to CD4+ helper T cells

Answer: II

Flashcard 5: The antigen receptors of T lymphocytes have one _____ and beta chain (monovalent)

Answer: alpha

Flashcard 6: father of immunology is

Answer: Edward Jenner louis pasteur is the father of bacteriology

Extra: 

Flashcard 7: IFN-gamma is produced by _____, NK cells, and CD8+ T cells; its primary function is the activation of macrophages.

Answer: Th1 cells

Flashcard 8: _____ cells are induced to kill cells that have an absence of MHC I on their cell surface

Answer: Natural killer

Flashcard 9: The enzymes responsible for gene recombination in heavy and light chains are encoded by the genes _____ and RAG2

Answer: RAG1

Flashcard 10: Mast cells can bind the _____ portion of IgE

Answer: Fc