Complement System — Flashcards

Flashcard 1: Which immunoglobulins cannot fix complement?_____

Answer: IgG4, IgA, IgD and IgE

Flashcard 2: _____ are the two primary opsonins in bacterial defense, which enhances phagocytosis

Answer: C3b and IgG

Flashcard 3: Ig_____ antibodies bind to the bacteria's capsule, resulting in either phagocytosis (Fc receptors) or binding of complement

Answer: G

Flashcard 4: Complement may be activated via the _____ pathway, which is mediated by IgM and IgG (immunoglobulins)

Answer: classic

Flashcard 5: Which B-cell receptor recognizes complement products during innate immune response?_____

Answer: CD21

Flashcard 6: _____ binds factor H and breaks down C3-convertase

Answer: M protein

Flashcard 7: father of immunology is

Answer: Edward Jenner louis pasteur is the father of bacteriology

Extra: 

Flashcard 8: _____ cells are induced to kill cells that have an absence of MHC I on their cell surface

Answer: Natural killer

Flashcard 9: The enzymes responsible for gene recombination in heavy and light chains are encoded by the genes _____ and RAG2

Answer: RAG1

Flashcard 10: IFN-gamma is produced by _____, NK cells, and CD8+ T cells; its primary function is the activation of macrophages.

Answer: Th1 cells