Immunology — Flashcards

The antigen receptors of B lymphocytes have two _____ and light chains (bivalent)

Mast cells can bind the _____ portion of IgE

T cell _____ antigens activate only mature B cells, monoclonally

Antibody _____ occurs via somatic hypermutation (point mutations in variable region genes).

Isotype switching is induced by cytokines, including _____ and IL-4.

Ig_____ exists as a pentamer held by a J chain when secreted

_____ is used as marker for the identification of memory T cells.

_____ are antigens that cross-link the Vβ region of T-cell receptors to MHC II on APCs outside the normal peptide-binding groove

Complement may be activated via the _____ pathway, which is mediated by mannose on microbial surfaces

Each B-cell expresses a light chain that is either a _____ or lambda isoform