Immunology — Flashcards

Natural killer cells may kill cells via binding between _____ (NK cells) and the Fc region of IgG-bound antigen

_____ cells are induced to kill cells that have an absence of MHC I on their cell surface

The enzymes responsible for gene recombination in heavy and light chains are encoded by the genes _____ and RAG2

IFN-gamma is produced by _____, NK cells, and CD8+ T cells; its primary function is the activation of macrophages.

Type 1 T-cell _____ antigens activate immature and mature B cells polyclonally

Isotype switching is induced by cytokines, including _____ and IL-4.

Ig_____ exists as a pentamer held by a J chain when secreted

T cell _____ antigens activate only mature B cells, monoclonally

Each B-cell expresses a light chain that is either a _____ or lambda isoform

Complement may be activated via the _____ pathway, which is mediated by mannose on microbial surfaces