NEET-PG 2013 Practice Questions

Q: Which of the following is not commonly used for local infiltration anesthesia?

Dibucaine. ***Dibucaine*** - **Dibucaine** is a local anesthetic with a long duration of action but is rarely used for local infiltration due to its **high toxicity**. - Its narrow therapeutic index makes it less safe for common use compared to other available local anesthetics. *Lidocaine* - **Lidocaine** is one of the most widely used local anesthetics for **local infiltration** due to its rapid onset and intermediate duration of action. - It is effective for a variety of minor surgical procedures and dental interventions. *Ropivacaine* - **Ropivacaine** is an amide-type local anesthetic commonly used for **local infiltration** and regional anesthesia due to its good safety profile and differential block. - It produces less motor block and has a lower potential for cardiotoxicity compared to bupivacaine. *Bupivacaine* - **Bupivacaine** is frequently used for **local infiltration** and regional anesthesia, especially when a longer duration of action is desired. - It is known for its prolonged sensory block but has a higher risk of **cardiac toxicity** compared to lidocaine.

Q: Which drug is most commonly associated with causing fixed drug eruptions?

Sulfonamide. ***Sulfonamide*** - **Sulfonamides**, particularly **sulfamethoxazole-trimethoprim**, are frequently implicated in causing fixed drug eruptions. - A fixed drug eruption characteristically recurs at the **same cutaneous site** each time the offending drug is administered. *Aminoglycoside* - **Aminoglycosides** are broad-spectrum antibiotics known for potential **ototoxicity** and **nephrotoxicity**. - While they can cause various adverse reactions, fixed drug eruptions are **not a common association** with this drug class. *Erythromycin* - **Erythromycin** is a macrolide antibiotic primarily associated with **gastrointestinal side effects**, such as nausea and abdominal cramping. - Although drug eruptions can occur, fixed drug eruptions are **not typically linked** to erythromycin. *None of the options* - This option is incorrect because **sulfonamides** are well-documented causes of fixed drug eruptions. - Therefore, there is a specific drug class listed that is strongly associated with this condition.

Q: Potato nose is seen in ?

Acne rosacea. ***Acne rosacea*** - **Potato nose**, also known as **rhinophyma**, is a severe manifestation of **acne rosacea**, characterized by thickened, red, and bumpy skin on the nose. - This condition results from **hyperplasia of sebaceous glands** and connective tissue in the nose, leading to its characteristic bulbous appearance. *Acne vulgaris* - This common skin condition is characterized by **comedones**, **papules**, **pustules**, and sometimes cysts, primarily on the face, chest, and back. - It does **not typically cause rhinophyma** or significant thickening of nasal skin. *Rhinosporoidosis* - This is a **chronic granulomatous fungal infection** affecting mucous membranes, particularly the nose. - While it can cause nasal polyps and masses, it does **not result in the sebaceous gland hyperplasia** and thickened skin characteristic of rhinophyma. *Lupus vulgaris* - Lupus vulgaris is a chronic and progressive form of **cutaneous tuberculosis**, often affecting the face. - It presents with **reddish-brown plaques** and nodules that can ulcerate and scar but does **not lead to the specific nasal hypertrophy** seen in rhinophyma.

Q: Which hormone is primarily responsible for insulin resistance during pregnancy?

HPL. ***HPL*** - **Human placental lactogen (HPL)**, also known as **chorionic somatomammotropin**, directly induces maternal insulin resistance to ensure a continuous supply of glucose to the fetus. - HPL levels rise throughout pregnancy, peaking in the third trimester, correlating with increasing insulin resistance. *Estrogen* - While **estrogen** levels are high in pregnancy, its primary role is in supporting uterine growth and maintaining the pregnancy, not directly causing significant insulin resistance. - High estrogen levels can enhance insulin sensitivity in some contexts, contrasting with the overall insulin resistance of pregnancy. *Progesterone* - **Progesterone** is crucial for maintaining pregnancy and relaxing smooth muscle but does not directly cause the marked insulin resistance seen in gestation. - It works synergistically with other hormones but is not the primary driver of glucose intolerance in pregnancy. *GH* - **Growth hormone (GH)** does contribute to insulin resistance in non-pregnant individuals and at high levels can cause insulin resistance, but it is not the primary hormone responsible for the unique physiological insulin resistance of pregnancy. - While GH is present, **HPL** is the dominant somatotropic hormone of pregnancy directly impacting glucose metabolism.

Q: Which drug is commonly used in the medical management of ectopic pregnancy?

Methotrexate. ***Correct: Methotrexate*** - **Methotrexate** is a **folic acid antagonist** that inhibits DNA synthesis and cell proliferation, making it effective in terminating early ectopic pregnancies by targeting rapidly dividing trophoblastic cells. - It is typically considered for **hemodynamically stable** patients with unruptured ectopic pregnancies, a beta-hCG level below a certain threshold (e.g., <5,000 mIU/mL), and no cardiac activity in the ectopic mass. - This is the **gold standard** for medical management of ectopic pregnancy meeting specific criteria. *Incorrect: Mifepristone* - **Mifepristone** is an **antiprogestin** primarily used for medical abortion of intrauterine pregnancies, causing detachment of the gestational sac and cervical ripening. - While it can be used in combination with misoprostol for medical abortion, it is **not the primary drug** for managing ectopic pregnancies. *Incorrect: Leuprolide* - **Leuprolide** is a **GnRH agonist** mainly used for conditions like endometriosis, uterine fibroids, and prostate cancer by suppressing ovarian or testicular hormone production. - It is **not used** in the direct medical management of ectopic pregnancy. *Incorrect: Carboprost* - **Carboprost** is a **prostaglandin F2-alpha analog** primarily used to treat **postpartum hemorrhage** by inducing strong uterine contractions. - It is **not indicated** for the treatment of ectopic pregnancy.

Q: Which drug is associated with decreased fetal heart rate during labor?

Oxytocin. ***Oxytocin*** - **Oxytocin** stimulates uterine contractions, which can reduce blood flow to the placenta and temporarily decrease **fetal oxygenation**, leading to **fetal heart rate decelerations**. - Overstimulation of the uterus by oxytocin can result in **tachysystole** (>5 contractions in 10 minutes), potentially causing **fetal hypoxia** and associated changes in fetal heart rate patterns such as late decelerations or bradycardia. *Sodium bicarbonate* - **Sodium bicarbonate** is used to correct metabolic acidosis, but it does not directly affect **fetal heart rate** or uterine activity in a way that causes decelerations. - Its administration is unlikely to impact fetal heart rate unless the underlying condition causing acidosis also affects fetal well-being, which is not a direct drug effect. *IV fluids* - **Intravenous fluids** are often administered during labor to maintain hydration and support maternal circulation, which generally helps improve **fetal well-being** and maintain normal fetal heart rate patterns. - They can help optimize **uterine perfusion**, thereby improving oxygen delivery to the fetus and reducing the risk of fetal distress. *Iron* - **Iron** is essential for red blood cell production and preventing maternal anemia; it has no direct or acute effect on **fetal heart rate** during labor. - Administered as a supplement, iron is not a medication used during labor to impact **uterine contractility** or fetal heart rate in the way oxytocin does.

Q: In the context of obstructed labor, which maternal pelvic parameter is considered the most critical for successful delivery?

Diameter of pelvic inlet. ***Diameter of pelvic inlet*** - The **pelvic inlet** is typically the narrowest and most critical passage for the fetal head to engage and descend into the pelvis during labor. - An inadequate pelvic inlet diameter can lead to **cephalopelvic disproportion**, resulting in **obstructed labor** because the fetal head cannot enter the true pelvis. *Diameter of pelvic outlet* - While important for the final stages of labor, an inadequate **pelvic outlet** usually presents a problem only after the fetal head has successfully navigated the inlet and mid-pelvis. - Obstruction at the outlet is less common as the primary cause of prolonged or arrested first stage labor compared to an unyielding inlet. *Biparietal diameter* - The **biparietal diameter (BPD)** measures the widest transverse diameter of the fetal head, which is crucial but represents a fetal parameter. - While critical for assessing fetal head size in relation to the maternal pelvis, it is a fetal measurement, not a maternal pelvic parameter like the inlet. *Bitemporal diameter* - The **bitemporal diameter** is the shortest transverse diameter of the fetal head and is rarely the presenting issue in **obstructed labor**. - It is typically much smaller than the biparietal diameter and usually presents no obstacle to passage through the pelvis.

Q: Von-Rosen's sign is positive in which of the following conditions?

Developmental Dysplasia of the Hip (DDH). ***Developmental Dysplasia of the Hip (DDH)*** - **Von-Rosen's sign** is a clinical test used to detect **instability or dislocation** of the hip in newborns, a hallmark of DDH. - The test involves placing the infant **supine with hips flexed to 90 degrees**, then **externally rotating and abducting** the hips while applying gentle longitudinal traction; positive if abduction is limited to **less than 60 degrees**. *Perthe's disease* - This condition involves **avascular necrosis of the femoral head** in children, typically presenting with a limp and hip pain, not congenital instability. - Diagnosis is usually made by X-rays showing **sclerosis and fragmentation** of the femoral head, not by Von-Rosen's sign. *SCFE* - **Slipped Capital Femoral Epiphysis (SCFE)** is a condition where the femoral head epiphysis displaces from the femoral neck, common in adolescents. - Patients typically present with **hip or knee pain** and a characteristic external rotation of the affected limb, which is not detected by Von-Rosen's sign. *CTEV* - **Congenital Talipes Equinovarus (CTEV)**, or **clubfoot**, is a deformity of the foot and ankle, involving plantarflexion and inversion. - This condition affects the foot, not the hip, rendering tests for hip instability like Von-Rosen's sign irrelevant.

Q: Which of the following can cause delirium?

All of the options. ***All of the options*** - **Delirium** is an acute, fluctuating disturbance in attention and cognition, often with altered consciousness, and can be caused by a wide range of factors. - **Hypoxia**, **barbiturate** use, and **alcohol withdrawal** are all well-established causes of delirium. *Hypoxia* - **Cerebral hypoxia**, or insufficient oxygen supply to the brain, directly impairs neuronal function, leading to acute confusion and altered mental status characteristic of delirium. - Conditions like severe respiratory failure, heart failure, or anemia can precipitate hypoxia and subsequent delirium. *Barbiturates* - **Barbiturates** are central nervous system depressants that can cause sedation, confusion, and cognitive impairment, especially in overdose or in susceptible individuals. - While they typically induce sedation, paradoxical excitement or severe cognitive dysfunction consistent with delirium can occur. *Alcohol withdrawal* - **Alcohol withdrawal** can lead to a severe form of delirium known as *delirium tremens*, characterized by extreme confusion, hallucinations, tremors, and autonomic instability. - The rapid cessation of chronic alcohol intake disrupts neurochemical balance, leading to hyperexcitability and delirium.

Question 1

Which of the following is not commonly used for local infiltration anesthesia?

Accepted Answer

Dibucaine

Answer

Lidocaine

Answer

Ropivacaine

Answer

Bupivacaine

Question 2

Which drug is most commonly associated with causing fixed drug eruptions?

Accepted Answer

Sulfonamide

Answer

Aminoglycoside

Answer

Erythromycin

Answer

None of the options

Question 3

Potato nose is seen in ?

Accepted Answer

Acne rosacea

Answer

Acne vulgaris

Answer

Rhinosporoidosis

Answer

Lupus vulgaris

Question 4

Which hormone is primarily responsible for insulin resistance during pregnancy?

Accepted Answer

HPL

Answer

Estrogen

Answer

Progesterone

Answer

GH

Question 5

Which drug is commonly used in the medical management of ectopic pregnancy?

Accepted Answer

Methotrexate

Answer

Leuprolide

Answer

Mifepristone

Answer

Carboprost

Question 6

Which drug is associated with decreased fetal heart rate during labor?

Accepted Answer

Oxytocin

Answer

Sodium bicarbonate

Answer

IV fluids

Answer

Iron

Question 7

In the context of obstructed labor, which maternal pelvic parameter is considered the most critical for successful delivery?

Accepted Answer

Diameter of pelvic inlet

Answer

Biparietal diameter

Answer

Bitemporal diameter

Answer

Diameter of pelvic outlet

Question 8

Von-Rosen's sign is positive in which of the following conditions?

Accepted Answer

Developmental Dysplasia of the Hip (DDH)

Answer

Perthe's disease

Answer

SCFE

Answer

CTEV

Question 9

Which of the following can cause delirium?

Accepted Answer

All of the options

Answer

Hypoxia

Answer

Barbiturates

Answer

Alcohol withdrawal

Question 10

What is an X-ray artifact?

Accepted Answer

An unwanted image distortion that doesn't represent actual anatomy

Answer

A radiographic finding that indicates disease pathology

Answer

A normal anatomical structure visible on X-ray

Answer

An image distortion produced when the patient moves during the X-ray procedure

NEET-PG 2013

Dental

Dermatology

Obstetrics and Gynecology

Orthopaedics

Psychiatry

Radiology