Anatomy
5 questionsWhat is the nerve supply of the larynx above the level of the vocal cords?
What is Galen's anastomosis?
Which muscle plays a role in winking?
Which of the following structures pass through the superior orbital fissure?
Which muscle is the deepest in the anterior neck region?
NEET-PG 2013 - Anatomy NEET-PG Practice Questions and MCQs
Question 371: What is the nerve supply of the larynx above the level of the vocal cords?
- A. Superior laryngeal (Correct Answer)
- B. Recurrent laryngeal
- C. Glossopharyngeal
- D. External laryngeal nerve
Explanation: ***Superior laryngeal*** - The **superior laryngeal nerve** branches into the internal and external laryngeal nerves. The **internal laryngeal nerve** (a branch of the superior laryngeal nerve) provides all sensory innervation to the larynx **above the vocal cords**. - It also carries **parasympathetic fibers** to the laryngeal glands in this region. *Recurrent laryngeal* - The **recurrent laryngeal nerve** provides sensory innervation to the larynx **below the vocal cords** [1]. - It also innervates all of the intrinsic muscles of the larynx except for the cricothyroid muscle [1]. *Glossopharyngeal* - The **glossopharyngeal nerve (CN IX)** primarily provides sensory innervation to the **posterior one-third of the tongue**, tonsils, pharynx, and middle ear. - It does not directly provide sensory innervation to the larynx. *External laryngeal nerve* - The **external laryngeal nerve**, a branch of the superior laryngeal nerve, is primarily **motor** and innervates the **cricothyroid muscle**. - It provides **no sensory innervation** to any part of the larynx.
Question 372: What is Galen's anastomosis?
- A. Recurrent laryngeal nerve and external laryngeal nerve
- B. Internal laryngeal nerve and recurrent laryngeal nerve (Correct Answer)
- C. None of the options
- D. Recurrent laryngeal nerve and sympathetic trunk
Explanation: ***Internal laryngeal nerve and recurrent laryngeal nerve*** - **Galen's anastomosis** (also known as **ansa Galeni**) is the connection between the **internal laryngeal nerve** (a sensory branch of the superior laryngeal nerve) and the **recurrent laryngeal nerve** (motor branch of the vagus nerve). - This anastomosis occurs in the **laryngeal mucosa** and allows for communication between these two important nerves. - The **internal laryngeal nerve** provides **sensory innervation** to the larynx above the vocal cords, while the **recurrent laryngeal nerve** provides **motor innervation** to most intrinsic laryngeal muscles (except cricothyroid). - This anastomosis is clinically significant in understanding the complex innervation patterns of the larynx. *Recurrent laryngeal nerve and external laryngeal nerve* - While both nerves are branches of the vagus nerve and innervate laryngeal structures, this connection does not constitute **Galen's anastomosis**. - The recurrent laryngeal nerve innervates intrinsic laryngeal muscles (except cricothyroid), while the external laryngeal nerve innervates the **cricothyroid muscle** and is motor in nature. *None of the options* - This option is incorrect because the correct definition of **Galen's anastomosis** is provided in the first option. *Recurrent laryngeal nerve and sympathetic trunk* - While there may be sympathetic contributions to laryngeal innervation, this does not represent **Galen's anastomosis**. - The sympathetic trunk provides autonomic innervation but the specific named anastomosis refers to the connection between the internal laryngeal and recurrent laryngeal nerves.
Question 373: Which muscle plays a role in winking?
- A. Levator labii superioris
- B. Orbicularis oculi (Correct Answer)
- C. Levator palpebrae
- D. Corrugator supercilii
Explanation: ***Orbicularis oculi*** - This muscle is responsible for **closing the eyelid** and is essential for actions like blinking, squinting, and winking. - Its fibers encircle the eye and facilitate the **controlled closure** required for winking. *Levator labii superioris* - This muscle primarily functions to **elevate the upper lip**, playing a role in facial expressions such as sneering or smiling. - It has no direct involvement in the movement of the eyelids or the act of winking. *Corrugator supercilii* - This muscle is located in the eyebrow region and is responsible for **drawing the eyebrows medially and inferiorly**, creating vertical wrinkles between the eyebrows. - It is associated with expressions of frowning or concern, not eyelid closure. *Levator palpebrae* - This muscle is responsible for **opening the upper eyelid**, thus counteracting the action of the orbicularis oculi. - While essential for eye movement, it is not involved in the closing action required for winking.
Question 374: Which of the following structures pass through the superior orbital fissure?
- A. Oculomotor nerve
- B. Trochlear nerve
- C. Superior ophthalmic vein
- D. All of the options (Correct Answer)
Explanation: ***All of the options*** - The **superior orbital fissure** is a key opening in the skull that allows passage of several important cranial nerves and vessels into the orbit. - The **oculomotor nerve**, **trochlear nerve**, and **superior ophthalmic vein** are all established structures that pass through this fissure. *Oculomotor nerve* - The **oculomotor nerve (CN III)** passes through the superior orbital fissure to innervate most of the extrinsic eye muscles. - It controls movements such as **adduction**, **elevation**, and **depression** of the eyeball, and also innervates the **levator palpebrae superioris** muscle for eyelid elevation [1]. *Trochlear nerve* - The **trochlear nerve (CN IV)**, which innervates the **superior oblique muscle**, also passes through the superior orbital fissure. - The superior oblique muscle is responsible for **intorsion** and **depression** of the eye, particularly when the eye is adducted [1]. *Superior ophthalmic vein* - The **superior ophthalmic vein** drains blood from structures within the orbit and passes through the superior orbital fissure to drain into the **cavernous sinus**. - This vein provides a connection between the facial veins and the cavernous sinus, which can be clinically relevant in cases of infection spread.
Question 375: Which muscle is the deepest in the anterior neck region?
- A. Sternocleidomastoid
- B. Platysma
- C. Longus colli (Correct Answer)
- D. Trapezius
Explanation: ***Longus colli*** - The **longus colli** muscle is the **deepest muscle** located in the anterior neck region, running along the front of the cervical vertebral column from C1 to T3. - It lies in the **prevertebral layer**, deep to all other anterior neck structures including the carotid sheath, visceral compartment, and superficial muscles. - Its position directly anterior to the vertebral bodies makes it the deepest anterior neck muscle. *Platysma* - The platysma is the **most superficial muscle** of the neck, located just beneath the skin in the superficial fascia. - It is not a deep muscle and lies superficial to all other neck muscles. *Sternocleidomastoid* - The sternocleidomastoid is enclosed within the **investing layer of deep cervical fascia**, making it relatively superficial. - While prominent in the anterior and lateral neck, it is not the deepest anterior neck muscle. *Trapezius* - The trapezius is a large, **superficial muscle of the back and posterior neck**. - It is not located in the anterior neck and is a superficial, not deep, muscle.
Biochemistry
5 questionsWhich of the following trace elements has vitamin E-like action?
What is the blood form of folic acid?
Which protein hormone is often referred to as the 'guardian angel against obesity' due to its role in regulating metabolism?
Which of the following organs does not primarily utilize fatty acids for energy?
Metabolic changes seen in starvation include all of the following except?
NEET-PG 2013 - Biochemistry NEET-PG Practice Questions and MCQs
Question 371: Which of the following trace elements has vitamin E-like action?
- A. Iron
- B. Selenium (Correct Answer)
- C. Copper
- D. Zinc
Explanation: ***Selenium*** - Selenium is an essential component of **glutathione peroxidase**, an enzyme that works alongside vitamin E to protect cells from **oxidative damage**. - Its antioxidant properties are similar to **vitamin E**, as both scavenge free radicals and prevent lipid peroxidation. *Iron* - Iron is vital for **oxygen transport** in hemoglobin and myoglobin, and for cellular respiration as a component of cytochromes. - While essential, iron does not have direct **antioxidant properties** akin to vitamin E; in excess, it can even promote oxidative stress. *Copper* - Copper is a cofactor for several enzymes, including **superoxide dismutase (SOD)**, an antioxidant enzyme, but its primary role is not directly analogous to vitamin E's lipid-soluble antioxidant function. - It also plays a role in **energy production**, iron metabolism, and neurotransmission. *Zinc* - Zinc is crucial for **immune function**, wound healing, and DNA synthesis, acting as a cofactor for over 300 enzymes. - Although it has indirect antioxidant effects by stabilizing cell membranes and reducing oxidative damage, its mechanism and direct action are not considered "vitamin E-like."
Question 372: What is the blood form of folic acid?
- A. Folinic acid
- B. Pteroglutamate
- C. Methyltetrahydrofolate (Correct Answer)
- D. None of the options
Explanation: ***Methyltetrahydrofolate*** - **5-methyltetrahydrofolate (5-MTHF)** is the **primary circulating form** of folate in the blood plasma and the most metabolically active form of folate. - It plays a crucial role in various metabolic pathways, especially in **one-carbon metabolism** for DNA synthesis and repair. *Folinic acid* - **Folinic acid** (leucovorin) is a **reduced form of folic acid** that does not require reduction by dihydrofolate reductase for activity. - It is often used as a therapeutic agent, particularly to **counteract the effects of methotrexate** toxicity, but it is not the main physiological circulating form. *Pteroglutamate* - **Pteroglutamate** is a generic term referring to compounds structurally related to folic acid, which is itself chemically known as pteroylglutamic acid. - While it describes the **general structure**, it is not the specific blood form of folic acid. *None of the options* - This option is incorrect because **methyltetrahydrofolate** is indeed the correct answer.
Question 373: Which protein hormone is often referred to as the 'guardian angel against obesity' due to its role in regulating metabolism?
- A. Adiponectin (Correct Answer)
- B. Fibronectin
- C. High-Density Lipoprotein (HDL)
- D. Insulin
Explanation: ***Adiponectin*** - **Adiponectin** is a hormone secreted by **adipose tissue** that plays a crucial role in regulating glucose and fatty acid metabolism, increasing **insulin sensitivity**, and decreasing inflammation. - Its levels are inversely correlated with body fat percentage; individuals with obesity tend to have lower adiponectin levels, leading to its nickname as the 'guardian angel against obesity'. *Fibronectin* - **Fibronectin** is a glycoprotein involved in cell adhesion, growth, migration, and differentiation, and is a key component of the **extracellular matrix**. - It does not primarily function in metabolic regulation or body weight control, unlike adiponectin. *High-Density Lipoprotein (HDL)* - **HDL** is a type of lipoprotein that transports cholesterol from peripheral tissues back to the liver, a process known as **reverse cholesterol transport**. - While beneficial for cardiovascular health, HDL is a lipid-carrying particle, not a protein hormone, and its primary role is not in metabolic regulation or direct obesity prevention. *Insulin* - **Insulin** is a peptide hormone produced by the pancreas that regulates carbohydrate and fat metabolism, primarily by facilitating glucose uptake from the blood into cells. - While essential for metabolism, high levels of insulin in the context of insulin resistance can contribute to obesity, rather than act against it.
Question 374: Which of the following organs does not primarily utilize fatty acids for energy?
- A. Brain (Correct Answer)
- B. Muscle
- C. Liver
- D. Kidney
Explanation: ***Brain*** - The **brain primarily uses glucose** as its main energy source because fatty acids cannot efficiently cross the **blood-brain barrier**. - During prolonged starvation, the brain can adapt to use **ketone bodies**, which are derived from fatty acid breakdown in the liver. *Muscle* - **Skeletal muscle** can utilize both **glucose and fatty acids** for energy, with fatty acids becoming a more prominent fuel source during prolonged exercise and at rest. - **Cardiac muscle** (heart) heavily relies on **fatty acid oxidation** as its primary energy substrate, especially during basal conditions. *Liver* - The **liver is highly metabolically flexible** and readily oxidizes fatty acids for its own energy needs, particularly during fasting states. - It also plays a key role in **fatty acid metabolism**, including synthesis, breakdown, and conversion into ketone bodies. *Kidney* - The **renal cortex** is rich in mitochondria and has a high metabolic rate, primarily utilizing **fatty acid oxidation** to meet its significant energy demands for filtration and reabsorption. - While the renal medulla can use glucose, the cortex's reliance on fatty acids makes it a significant consumer.
Question 375: Metabolic changes seen in starvation include all of the following except?
- A. Ketogenesis
- B. Protein degradation
- C. Increased gluconeogenesis
- D. Increased glycolysis (Correct Answer)
Explanation: ***Increased glycolysis*** - In starvation, the body's primary goal is to conserve **glucose** for essential organs like the brain, as glucose supply is limited. Therefore, glycolysis, the breakdown of glucose, is *decreased*, not increased. - The body shifts to using alternative fuels such as **fatty acids** and **ketone bodies** to spare glucose. *Increased gluconeogenesis* - **Gluconeogenesis**, the synthesis of glucose from non-carbohydrate precursors like amino acids and glycerol, is *increased* during starvation to maintain blood glucose levels. - This process is crucial for providing glucose to tissues that primarily rely on it, such as the brain and red blood cells. *Ketogenesis* - **Ketogenesis**, the production of ketone bodies from fatty acids, is significantly *increased* during prolonged starvation. - **Ketone bodies** become a major energy source for the brain and other tissues when glucose is scarce, helping to spare muscle protein. *Protein degradation* - **Protein degradation** (proteolysis) is *increased* during starvation, especially in the initial phases, to provide amino acids for gluconeogenesis. - Muscle protein is a primary source of these amino acids, contributing to muscle wasting observed in prolonged starvation.