Anatomy
6 questionsWhich of the following statements about the linea aspera is correct?
Which of the following statements about the great saphenous vein is true?
Interosseous membrane of forearm is pierced by?
Which muscles are known as 'Triceps surae'?
Which muscle is attached to the lateral surface of the greater trochanter?
What is the nerve supply to the muscles of the flexor compartment of the arm?
NEET-PG 2013 - Anatomy NEET-PG Practice Questions and MCQs
Question 261: Which of the following statements about the linea aspera is correct?
- A. Forms lateral border of femur
- B. Continues as gluteal tuberosity (Correct Answer)
- C. Forms medial border of femur
- D. None of the options
Explanation: Correct: Continues as gluteal tuberosity - The lateral lip of the linea aspera continues superiorly as the gluteal tuberosity (also called the gluteal ridge or line) - This anatomical continuation is a key feature of the femur's posterior surface - The gluteal tuberosity serves as the attachment site for the gluteus maximus muscle - The medial lip continues superiorly as the pectineal line (spiral line), which then joins the lesser trochanter Incorrect: Forms lateral border of femur - The linea aspera is located on the posterior surface of the femoral shaft, not on the lateral border - The lateral border of the femur is formed by the smooth lateral surface of the shaft - The linea aspera's lateral lip is a posterior ridge, distinct from the true lateral border Incorrect: Forms medial border of femur - The linea aspera is on the posterior aspect of the femur, not the medial border - The medial border of the femur is formed by the smooth medial surface of the shaft - The medial lip of the linea aspera is a muscle attachment site on the posterior surface, not a border
Question 262: Which of the following statements about the great saphenous vein is true?
- A. It begins at lateral end of dorsal venous arch
- B. It runs anterior to medial malleolus (Correct Answer)
- C. Terminates into popliteal vein
- D. It is accompanied by the sural nerve
Explanation: **It runs anterior to medial malleolus** - The **great saphenous vein** originates from the medial end of the **dorsal venous arch** of the foot and ascends anterior to the **medial malleolus** [1]. - This anatomical relationship makes it accessible for various clinical procedures, such as **venous cutdown** for rapid intravenous access [1]. *It begins at lateral end of dorsal venous arch* - The **great saphenous vein** actually begins at the **medial end** of the dorsal venous arch, not the lateral end [1]. - The **small saphenous vein** arises from the lateral end of the dorsal venous arch [1]. *It is accompanied by the sural nerve* - The **sural nerve** typically accompanies the **small saphenous vein**, not the great saphenous vein, in the posterior leg [1]. - The **saphenous nerve**, a branch of the femoral nerve, accompanies the great saphenous vein throughout its course in the leg. *Terminates into popliteal vein* - The **great saphenous vein** normally terminates by draining into the **femoral vein** in the femoral triangle, not the popliteal vein [1]. - The **small saphenous vein** is the one that typically drains into the popliteal vein [1].
Question 263: Interosseous membrane of forearm is pierced by?
- A. Brachial artery
- B. Anterior interosseous artery (Correct Answer)
- C. Posterior interosseous artery
- D. Ulnar recurrent artery
Explanation: ***Anterior interosseous artery*** - The **anterior interosseous artery** pierces the **interosseous membrane** in the **distal forearm** (approximately 5 cm above the wrist) to anastomose with the **posterior interosseous artery** and contribute to the **palmar carpal arch**. - This artery arises from the **common interosseous artery**, a branch of the **ulnar artery**. - This is the **classically taught structure** that pierces the interosseous membrane and is the standard answer in examination contexts. *Brachial artery* - The **brachial artery** is the main artery of the arm and terminates in the **cubital fossa** by dividing into the **radial** and **ulnar arteries**. - It does not pierce the **interosseous membrane** of the forearm as it is located in the arm, not the forearm. *Posterior interosseous artery* - The **posterior interosseous artery** arises from the **common interosseous artery** and passes **posteriorly between the oblique cord and the upper border of the interosseous membrane** to enter the posterior compartment of the forearm. - While it may pierce the membrane distally to anastomose anteriorly, the **anterior interosseous artery** is the structure **classically described** as piercing the membrane in standard anatomical teaching and examination contexts. *Ulnar recurrent artery* - The **ulnar recurrent arteries** (anterior and posterior branches) arise from the **ulnar artery** near the **cubital fossa** and ascend to participate in the **anastomosis around the elbow joint**. - These arteries do not pierce the **interosseous membrane** of the forearm.
Question 264: Which muscles are known as 'Triceps surae'?
- A. Popliteus
- B. Extensor hallucis longus
- C. Extensor digitorum longus
- D. Gastro-soleus (Correct Answer)
Explanation: ***Gastro-soleus*** - The **Triceps surae** refers to the two heads of the **gastrocnemius muscle** and the **soleus muscle**, which together form the powerful calf muscle. - These three muscles converge to form the **Achilles tendon** (calcaneal tendon) and are prime movers for **plantarflexion** of the ankle. *Popliteus* - The popliteus muscle is located behind the knee joint and acts to **unlock the knee** during flexion. - It does not contribute to the bulk of the calf and is not part of the Triceps surae group. *Extensor hallucis longus* - This muscle is located in the **anterior compartment** of the leg and is responsible for **dorsiflexion** of the ankle and extension of the great toe. - It is an antagonist to the Triceps surae, which primarily performs plantarflexion. *Extensor digitorum longus* - The extensor digitorum longus is also in the **anterior compartment** of the leg, responsible for **dorsiflexion** of the ankle and extension of the lateral four toes. - It is functionally opposite to the actions of the Triceps surae and in a different muscle compartment.
Question 265: Which muscle is attached to the lateral surface of the greater trochanter?
- A. Gluteus maximus
- B. Gluteus medius (Correct Answer)
- C. Gluteus minimus
- D. Piriformis
Explanation: ***Gluteus medius*** - The **gluteus medius** inserts onto the **lateral surface of the greater trochanter** of the femur. - Its primary actions include **abduction** and **internal rotation** of the hip. *Gluteus maximus* - The **gluteus maximus** inserts primarily into the **iliotibial tract** and the **gluteal tuberosity** of the posterior femur, not the lateral greater trochanter. - Its main roles are **hip extension** and **external rotation**. *Gluteus minimus* - The **gluteus minimus** inserts onto the **anterior part of the lateral surface (anterolateral aspect)** of the greater trochanter, anterior to the gluteus medius insertion. - Like the gluteus medius, it also contributes to **hip abduction** and **internal rotation**. *Piriformis* - The **piriformis** muscle inserts onto the **superior and medial aspect of the greater trochanter**. - Its main actions are **external rotation** and **abduction** of the hip, particularly when the hip is flexed.
Question 266: What is the nerve supply to the muscles of the flexor compartment of the arm?
- A. Musculocutaneous nerve (Correct Answer)
- B. Median nerve
- C. Radial nerve
- D. Ulnar nerve
Explanation: ***Musculocutaneous nerve*** - The **musculocutaneous nerve** is the primary nerve supplying all three muscles in the **flexor compartment of the arm**: the **biceps brachii**, **brachialis**, and **coracobrachialis**. - Its motor branches innervate these muscles, allowing for **flexion at the elbow** and **supination of the forearm**. *Median nerve* - The **median nerve** primarily innervates most muscles in the **flexor compartment of the forearm**, not the arm. - It plays a crucial role in **wrist and finger flexion**, as well as movements of the **thenar eminence**. *Radial nerve* - The **radial nerve** is the main nerve for the **extensor compartment of the arm and forearm**. - It is responsible for **elbow, wrist, and finger extension**. *Ulnar nerve* - The **ulnar nerve** primarily supplies intrinsic muscles of the hand and some flexor muscles in the forearm. - It has no motor supply to the muscles of the **flexor compartment of the arm**.
Internal Medicine
1 questionsWhat is the primary condition associated with positive anti-dsDNA antibodies?
NEET-PG 2013 - Internal Medicine NEET-PG Practice Questions and MCQs
Question 261: What is the primary condition associated with positive anti-dsDNA antibodies?
- A. RA
- B. SLE (Correct Answer)
- C. Scleroderma
- D. PAN
Explanation: ***SLE*** - **Anti-dsDNA antibodies** are a highly specific marker for **Systemic Lupus Erythematosus (SLE)** and are included in its diagnostic criteria [1]. - The levels of **anti-dsDNA antibodies** can also correlate with disease activity, particularly in cases of **lupus nephritis** [1]. *RA* - **Rheumatoid Arthritis (RA)** is primarily associated with **rheumatoid factor (RF)** and **anti-citrullinated protein antibodies (ACPA)** or **anti-CCP antibodies**. - While ANA (antinuclear antibodies) can be positive in RA, **anti-dsDNA antibodies** are not a characteristic serological marker [1]. *Scleroderma* - **Scleroderma**, or systemic sclerosis, is characterized by specific antibodies such as **anti-Scl-70 (topoisomerase I)**, **anti-centromere antibodies**, and **anti-RNA polymerase III antibodies**, depending on the subtype. - **Anti-dsDNA antibodies** are not typically found in scleroderma and do not play a role in its diagnosis [1]. *PAN* - **Polyarteritis Nodosa (PAN)** is a **necrotizing vasculitis** of medium-sized arteries and is not associated with **anti-dsDNA antibodies**. - PAN is generally considered an **ANCA-negative vasculitis**, and its diagnosis relies more on clinical features, angiography, and biopsy findings.
Microbiology
1 questionsWhich cytokine activates macrophages?
NEET-PG 2013 - Microbiology NEET-PG Practice Questions and MCQs
Question 261: Which cytokine activates macrophages?
- A. Leukotriene B4
- B. IL-8
- C. IFN-γ (Correct Answer)
- D. PAF
Explanation: ***IFN-γ (Interferon-gamma)*** - **IFN-γ is the classic macrophage-activating cytokine**, enhancing phagocytic and antimicrobial functions - Promotes expression of **MHC class I and II molecules**, increasing antigen presentation capacity - Produced mainly by **Th1 cells and NK cells** during cell-mediated immunity - Key cytokine in defense against **intracellular pathogens** (mycobacteria, viruses) *IL-8* - **IL-8 is a chemokine** (cytokine subfamily) primarily involved in **neutrophil chemotaxis** - Recruits neutrophils to sites of infection or inflammation - Does not directly activate macrophages like IFN-γ - Important in acute inflammatory responses *PAF (Platelet-Activating Factor)* - **Not a cytokine** - it is a **phospholipid mediator** - Involved in allergic and inflammatory responses - Functions include **platelet aggregation**, **vasodilation**, and **bronchoconstriction** - While it affects immune responses, it doesn't function as a macrophage-activating cytokine *Leukotriene B4* - **Not a cytokine** - it is a **lipid mediator** (eicosanoid) derived from arachidonic acid - Primarily acts as a **chemoattractant for neutrophils** - Promotes neutrophil and monocyte adhesion and migration to inflammatory sites - Does not directly activate macrophages
Pathology
2 questionsAll of the following are true regarding fibromuscular dysplasia EXCEPT:
Which of the following statements about wound healing is false?
NEET-PG 2013 - Pathology NEET-PG Practice Questions and MCQs
Question 261: All of the following are true regarding fibromuscular dysplasia EXCEPT:
- A. Medium size vessels are affected
- B. Aneurysm may occur
- C. Irregular hyperplasia
- D. OCPs predispose (Correct Answer)
Explanation: ***OCPs predispose*** - **Oral contraceptive pills (OCPs)** are not identified as a predisposing factor for fibromuscular dysplasia (FMD). FMD is largely considered a sporadic condition with some genetic predisposition, but not linked to OCP use [1]. - While hormonal influences are suspected given its higher prevalence in women, direct causation or exacerbation by OCPs has not been established [1]. *Medium size vessels are affected* - Fibromuscular dysplasia (FMD) predominantly affects **medium-sized arteries**, most commonly the renal and carotid arteries [1]. - This involvement leads to characteristic stenoses, aneurysms, or dissections in those vessels. *Aneurysm may occur* - The abnormal arterial wall architecture in FMD, characterized by alternating areas of stenosis and dilation, can lead to the formation of **aneurysms**. - These aneurysms are usually **intracranial** or within the affected renal and carotid arteries, and represent a significant risk of rupture or dissection. *Irregular hyperplasia* - FMD involves **irregular fibrous or fibromuscular hyperplasia** of the arterial wall layers (intima, media, or adventitia). - This abnormal cellular proliferation and connective tissue deposition result in the characteristic "string of beads" appearance on angiography. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Diseases of Infancy and Childhood, pp. 493-494.
Question 262: Which of the following statements about wound healing is false?
- A. Inhibited by diabetes mellitus (DM)
- B. Inhibited by foreign body
- C. Hematomas promote wound healing (Correct Answer)
- D. Inhibited by infection
Explanation: ***Hematomas promotes wound healing*** - Hematomas (localized collections of **blood outside blood vessels**) actually **inhibit wound healing** by acting as a medium for bacterial growth and increasing tissue tension. - This statement is **false** because hematomas interfere with proper tissue apposition and oxygen delivery, which are crucial for successful wound repair [3]. *Inhibited by diabetes mellitus (DM)* - **Diabetes mellitus** impairs various stages of wound healing due to **poor glycemic control**, leading to compromised immune function, neuropathy, and reduced blood flow [1]. - This often results in **delayed wound closure** and increased risk of infection [2]. *Inhibited by foreign body* - The presence of a **foreign body** in a wound can lead to a persistent inflammatory response, impeding tissue repair and increasing the likelihood of chronic infection. - This sustained inflammation prevents the orderly progression through the phases of wound healing, thus **inhibiting the process**. *Inhibited by infection* - **Infection** in a wound significantly delays healing by causing ongoing inflammation, tissue destruction, and increased metabolic demands [1]. - Bacteria compete for nutrients and produce toxins that harm host cells, preventing proper **granulation tissue formation** and **epithelialization**. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Inflammation and Repair, pp. 116-117. [2] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. (Basic Pathology) introduces the student to key general principles of pathology, both as a medical science and as a clinical activity with a vital role in patient care. Part 2 (Disease Mechanisms) provides fundamental knowledge about the cellular and molecular processes involved in diseases, providing the rationale for their treatment. Part 3 (Systematic Pathology) deals in detail with specific diseases, with emphasis on the clinically important aspects., pp. 110-111. [3] Cross SS. Underwood's Pathology: A Clinical Approach. 6th ed. (Basic Pathology) introduces the student to key general principles of pathology, both as a medical science and as a clinical activity with a vital role in patient care. Part 2 (Disease Mechanisms) provides fundamental knowledge about the cellular and molecular processes involved in diseases, providing the rationale for their treatment. Part 3 (Systematic Pathology) deals in detail with specific diseases, with emphasis on the clinically important aspects., pp. 106-107.