Anatomy
7 questionsWhat is the largest branch of the brachial plexus?
A person had injury to right upper limb, he is not able to extend fingers but able to extend wrist and elbow. Nerve injured is ?
How many ossification centers develop at the distal end of the humerus?
Which of the following statements regarding axillary lymph nodes is incorrect?
Which of the following muscles is not in the pectoral region?
Which is the primary muscle causing supination of the forearm?
All are supplied by the anterior interosseous nerve except which of the following?
NEET-PG 2013 - Anatomy NEET-PG Practice Questions and MCQs
Question 181: What is the largest branch of the brachial plexus?
- A. Ulnar nerve
- B. Radial nerve (Correct Answer)
- C. Axillary nerve
- D. Median nerve
Explanation: ***Radial nerve*** - The **radial nerve** is considered the largest branch of the brachial plexus due to its extensive innervation of numerous muscles in the posterior compartment of the arm and forearm. - It arises from the **posterior cord** of the brachial plexus and innervates all the extensors of the arm and forearm, including the triceps brachii and supinator. *Ulnar nerve* - The ulnar nerve is a significant branch, but it is **smaller** in cross-sectional area and muscular distribution compared to the radial nerve. - It mainly innervates muscles of the **hand** and some forearm flexors. *Median nerve* - The median nerve is a large and clinically important nerve, formed by contributions from both the **lateral and medial cords**, but it is generally *not* considered the largest in terms of overall bulk or number of muscular branches. - It primarily innervates the **flexor muscles of the forearm** and some muscles of the hand (thenar eminence). *Axillary nerve* - The axillary nerve is one of the **smaller** terminal branches of the brachial plexus. - It primarily innervates the **deltoid** and **teres minor muscles**, and a small area of skin over the shoulder.
Question 182: A person had injury to right upper limb, he is not able to extend fingers but able to extend wrist and elbow. Nerve injured is ?
- A. Median
- B. Ulnar
- C. Radial
- D. Posterior interosseous (Correct Answer)
Explanation: ***Posterior interosseous*** - This nerve supplies the muscles responsible for **finger extension**, such as the **extensor digitorum**, **extensor indicis**, and **extensor digiti minimi**. - A lesion here would spare wrist and elbow extension because the nerves to the **extensor carpi radialis longus/brevis** and **triceps brachii** branch off the radial nerve proximal to the origin of the posterior interosseous nerve. *Radial* - A more proximal **radial nerve injury** would result in the inability to extend the wrist (leading to **wrist drop**), fingers, and thumb, which is not seen here as wrist extension is preserved. - It also innervates the **triceps brachii**, and a high radial nerve injury would affect elbow extension; this patient can extend their elbow. *Median* - The **median nerve** primarily innervates muscles responsible for **flexion** of the wrist and fingers, as well as **thumb opposition** and **pronation**. - Its injury would not directly lead to an inability to extend the fingers, but rather weakness in flexion and specific thumb movements. *Ulnar* - The **ulnar nerve** innervates most of the **intrinsic hand muscles** and the **flexor carpi ulnaris**, leading to weakness in finger abduction/adduction and flexion of the 4th and 5th digits. - It does not control finger extension, so an injury would not cause this specific deficit.
Question 183: How many ossification centers develop at the distal end of the humerus?
- A. 2
- B. 3 (Correct Answer)
- C. 5
- D. 4
Explanation: ***3*** - The distal end of the humerus develops **three primary ossification centers**: the capitellum, trochlea, and medial epicondyle [1]. - These centers appear sequentially and their ossification pattern is important for assessing **skeletal maturity** in children using the CRITOE mnemonic [1]. - The capitellum appears at 1 year, medial epicondyle at 5 years, and trochlea at 9 years. *2* - This number is too low and only accounts for the **capitellum and medial epicondyle**, missing the trochlea. - While these are the first two to appear, there is an additional primary ossification center (trochlea) that develops later. *5* - This number is incorrect; there are only **three primary ossification centers** at the distal humerus, not five. - This may cause confusion with other joints or by counting secondary ossification centers. *4* - This number is incorrect; while the lateral epicondyle does ossify, it is not consistently counted as a **primary ossification center**. - The standard anatomical teaching recognizes **three primary centers**: capitellum, trochlea, and medial epicondyle.
Question 184: Which of the following statements regarding axillary lymph nodes is incorrect?
- A. Posterior group lies along subscapular vessels
- B. Lateral group lies along lateral thoracic vessels (Correct Answer)
- C. Apical group is terminal lymph nodes
- D. Apical group lies along axillary vessels
Explanation: ***Lateral group lies along lateral thoracic vessels*** - The **lateral group** of axillary lymph nodes is located along the **axillary vein**, receiving lymph primarily from the upper limb [1]. - The **lateral thoracic vessels** are associated with the central and posterior groups of axillary lymph nodes, not the lateral group. *Posterior group lies along subscapular vessels* - The **posterior (subscapular) group** of axillary lymph nodes is indeed located along the **subscapular vessels**. - This group receives lymph from the posterior wall of the trunk and the posterior shoulder region. *Apical group is terminal lymph nodes* - The **apical group** (also known as the subclavian group) is considered the **terminal lymph nodes** of the axilla. - Lymph from all other axillary nodes eventually drains into the apical group before continuing to the supraclavicular nodes and then into the subclavian lymphatic trunk [2]. *Apical group lies along axillary vessels* - The **apical group** of axillary lymph nodes is situated in the apex of the axilla, superior to the pectoralis minor muscle, and lies in close proximity to the **axillary vessels** [1]. - This location allows it to receive lymph from other axillary groups and drain into the supraclavicular lymph nodes.
Question 185: Which of the following muscles is not in the pectoral region?
- A. Pectoralis major
- B. Infraspinatus (Correct Answer)
- C. Pectoralis minor
- D. Subclavius
Explanation: ***Infraspinatus*** - The **infraspinatus** muscle is located in the **posterior scapular region**, specifically on the posterior aspect of the scapula, filling the infraspinous fossa. - Its primary function is **external rotation** of the humerus, and it is a key component of the **rotator cuff**. *Pectoralis major* - The **pectoralis major** is a large, superficial muscle located in the **anterior chest wall**, forming the bulk of the chest. [1] - It plays a significant role in **adduction**, **flexion**, and **medial rotation** of the humerus. *Pectoralis minor* - The **pectoralis minor** is a smaller, triangular muscle situated beneath the pectoralis major in the **anterior thoracic wall**. [1] - Its functions include **stabilizing the scapula** by pulling it inferiorly and anteriorly, and assisting in forced inspiration. [1] *Subclavius* - The **subclavius** is a small, triangular muscle located inferior to the clavicle in the **pectoral region**. - Its primary role is to **depress and stabilize the clavicle**, protecting the underlying neurovascular structures.
Question 186: Which is the primary muscle causing supination of the forearm?
- A. Brachioradialis
- B. Anconeus
- C. Biceps brachii
- D. Supinator (Correct Answer)
Explanation: ***Supinator*** - The **supinator muscle** is the **primary muscle** responsible for **supination** of the forearm, rotating the palm anteriorly or superiorly. - It is a deep muscle of the **posterior compartment** of the forearm. - Its action is especially prominent when **supinating against resistance** or in very slow movements, as it works synergistically with the biceps brachii. *Biceps brachii* - While the **biceps brachii** is also a powerful **supinator** of the forearm, especially when the elbow is flexed, it is a **secondary supinator**. - It is primarily a major **flexor** of the elbow, whereas the supinator is dedicated specifically to supination. *Brachioradialis* - The **brachioradialis** is primarily a **flexor** of the forearm at the elbow joint. - It helps to bring the forearm into a **mid-prone or mid-supine position** from either full pronation or full supination, but does not actively supinate. *Anconeus* - The **anconeus** is a small muscle that assists the **triceps brachii** in **extension of the forearm** at the elbow. - It helps to **stabilize the elbow joint** and slightly abducts the ulna during pronation, but has no role in supination.
Question 187: All are supplied by the anterior interosseous nerve except which of the following?
- A. Flexor carpi ulnaris (Correct Answer)
- B. Pronator quadratus
- C. Flexor digitorum profundus (lateral half)
- D. Flexor pollicis longus
Explanation: ***Flexor carpi ulnaris*** - The **flexor carpi ulnaris** (FCU) is innervated by the **ulnar nerve**, not the anterior interosseous nerve [1]. - This is the correct answer as it is NOT supplied by the AIN. *Pronator quadratus* - The **pronator quadratus** IS supplied by the **anterior interosseous nerve**. - This deep muscle is responsible for **pronation of the forearm** and is one of the three muscles innervated by the AIN. *Flexor digitorum profundus (lateral half)* - The **lateral half of flexor digitorum profundus** (to index and middle fingers) IS supplied by the **anterior interosseous nerve**. - The medial half (to ring and little fingers) is supplied by the ulnar nerve. *Flexor pollicis longus* - The **flexor pollicis longus** (FPL) IS supplied by the **anterior interosseous nerve**. - This muscle is responsible for **flexion of the thumb's interphalangeal joint** and is one of the three muscles innervated by the AIN.
Pharmacology
2 questionsWhich of the following is a second-generation beta blocker?
Muscarinic cholinergic receptors are seen at all sites, except?
NEET-PG 2013 - Pharmacology NEET-PG Practice Questions and MCQs
Question 181: Which of the following is a second-generation beta blocker?
- A. Timolol
- B. Atenolol (Correct Answer)
- C. Nadolol
- D. Propranolol
Explanation: ***Atenolol*** - **Atenolol** is a **second-generation beta blocker** characterized by its **cardioselectivity**, meaning it primarily blocks beta-1 receptors in the heart. - This selectively reduces heart rate and contractility with fewer respiratory side effects compared to non-selective agents. *Propranolol* - **Propranolol** is a **first-generation non-selective beta blocker**, meaning it blocks both beta-1 and beta-2 adrenergic receptors. - Its non-selective action can cause significant bronchoconstriction, making it less suitable for patients with respiratory conditions. *Timolol* - **Timolol** is also a **first-generation non-selective beta blocker** commonly used in ophthalmic preparations for glaucoma. - It blocks both beta-1 and beta-2 receptors and does not possess the cardioselectivity of second-generation agents. *Nadolol* - **Nadolol** is another **first-generation non-selective beta blocker** with a long duration of action due to its extensive plasma half-life. - Like other first-generation agents, it lacks cardioselectivity and blocks both beta-1 and beta-2 receptors.
Question 182: Muscarinic cholinergic receptors are seen at all sites, except?
- A. Stomach
- B. CNS
- C. Glands
- D. Neuromuscular junction (Correct Answer)
Explanation: ***Neuromuscular junction*** - The **neuromuscular junction** primarily contains **nicotinic cholinergic receptors**, not muscarinic receptors. - Activation of these nicotinic receptors by acetylcholine causes muscle contraction. *Stomach* - The stomach contains **muscarinic M3 receptors** which mediate gastric acid secretion and smooth muscle contraction. - Activation by acetylcholine via the vagus nerve promotes digestion. *CNS* - The **central nervous system** has various subtypes of **muscarinic receptors (M1-M5)** distributed throughout, playing roles in learning, memory, and motor control. - These receptors modulate neuronal excitability and neurotransmitter release. *Glands* - Most exocrine glands (e.g., salivary, lacrimal, sweat glands) are richly supplied with **muscarinic receptors**, primarily **M3**. - Activation leads to increased glandular secretion.
Psychiatry
1 questionsWhich of the following develop first during dependence of a substance ?
NEET-PG 2013 - Psychiatry NEET-PG Practice Questions and MCQs
Question 181: Which of the following develop first during dependence of a substance ?
- A. Tolerance
- B. Physical dependence
- C. Psychological dependence (Correct Answer)
- D. Withdrawal symptoms
Explanation: ***Psychological dependence*** - **Psychological dependence** often develops first, characterized by an emotional need for the substance to experience pleasure or avoid discomfort. - This involves a strong **craving** and compulsive drug-seeking behavior despite negative consequences, driven by the substance's effect on brain reward pathways. *Tolerance* - **Tolerance** means that increasing doses of the substance are required to achieve the same effect previously achieved with lower doses. - While it often develops early in substance use, the initial "need" to use the substance is often psychological before physiological adaptations occur. *Physical dependence* - **Physical dependence** describes the body's physiological adaptation to the substance, leading to withdrawal symptoms if use is stopped or reduced. - It typically develops after consistent, prolonged use and is usually preceded by psychological dependence and often tolerance. *Withdrawal symptoms* - **Withdrawal symptoms** are the physiological and psychological signs that occur when a dependent person stops or drastically reduces their substance intake. - These are a direct manifestation of physical dependence and thus develop once physical dependence has been established.