NEET-PG 2013 Practice Questions

Q: What is the definition of conscious sedation?

Sedation with ability to respond to verbal commands. ***Sedation with ability to respond to verbal commands*** - Conscious sedation involves a drug-induced depression of consciousness during which the patient **retains the ability to respond purposefully to verbal commands**. - This level of sedation ensures that the patient's **airway reflexes** and **ventilatory function** remain intact. *CNS depression with unconsciousness* - This describes **general anesthesia** or **deep sedation**, where the patient is unable to respond purposefully to verbal commands. - In such states, spontaneous ventilation may be **inadequate**, and **airway support** is often required. *Sedation with inability to respond to verbal commands* - This definition aligns with **deep sedation** or **general anesthesia**, where the patient's consciousness is significantly depressed. - At this level, patients may require assistance in maintaining a **patent airway** and adequate ventilation. *None of the options* - This option is incorrect because one of the provided definitions accurately describes conscious sedation. - The definition of conscious sedation is well-established in clinical practice, emphasizing the **preservation of responsiveness**.

Q: Which of the following drugs is effective in the treatment of pityriasis versicolor?

Ketoconazole. ***Ketoconazole*** - **Ketoconazole** is an **azoles antifungal agent** effective against the *Malassezia* species, the causative agent of **pityriasis versicolor**. - It works by inhibiting the synthesis of **ergosterol**, a crucial component of the fungal cell membrane, leading to its disruption and fungal cell death. *Metronidazole* - **Metronidazole** is an **antibiotic** and **amoebicide** primarily used to treat bacterial and parasitic infections. - It has **no antifungal activity** and is thus ineffective against *Malassezia* or other fungal infections. *Griseofulvin* - **Griseofulvin** is an **oral antifungal drug** primarily used for **dermatophyte infections** of the skin, hair, and nails (e.g., tinea capitis, onychomycosis). - It is **ineffective against yeasts and molds**, including *Malassezia*, making it unsuitable for pityriasis versicolor. *Chloroquine* - **Chloroquine** is an **antimalarial drug** also used in the treatment of some autoimmune conditions like lupus erythematosus. - It possesses **no antifungal properties** and is not used to treat fungal infections of any kind.

Q: In a patient with heart disease, which condition is most commonly associated with left atrial enlargement?

Mitral stenosis. ***Mitral stenosis*** - **Mitral stenosis** leads to an obstruction of blood flow from the **left atrium to the left ventricle**, causing pressure buildup in the left atrium [1]. - This increased pressure over time results in **left atrial enlargement** as the chamber struggles to push blood through the narrowed valve [1]. *Tricuspid regurgitation* - **Tricuspid regurgitation** involves the backflow of blood from the **right ventricle to the right atrium**. - This condition primarily affects the **right side of the heart**, leading to **right atrial enlargement**, not left. *AR* - **Aortic regurgitation (AR)** is the backflow of blood from the **aorta into the left ventricle**. - While AR can cause **left ventricular enlargement** and eventually lead to left atrial dilation, it is not the most common direct cause of *primary* left atrial enlargement compared to mitral stenosis [2]. *None of the options* - **Mitral stenosis** is a well-established cause of significant left atrial enlargement due to the direct pressure overload it imposes on the left atrium [1].

Q: Most common presentation of cervical cancer is -

Abnormal vaginal bleeding. ***Abnormal vaginal bleeding*** - **Abnormal vaginal bleeding** is the most frequent presenting symptom of cervical cancer, often manifesting as **postcoital bleeding**, intermenstrual bleeding, or heavier, longer menstrual periods. - This symptom arises as the tumor on the cervix ulcerates and bleeds due to its friable nature and rich vascularization. *Pelvic pain* - **Pelvic pain** is typically a symptom of more **advanced cervical cancer**, indicating tumor invasion into surrounding tissues or nerves. - It is not usually an early or the most common presenting symptom, unlike abnormal bleeding. *Pain during intercourse* - **Pain during intercourse (dyspareunia)** can be a symptom of cervical cancer, particularly with larger lesions or those causing inflammation. - However, it is less common than abnormal bleeding and often occurs concurrently with or after the onset of bleeding symptoms. *Unusual vaginal discharge* - An **unusual vaginal discharge**, which may be watery, foul-smelling, or blood-tinged, can occur with cervical cancer. - While a common symptom, it is generally considered less frequent than abnormal vaginal bleeding as the primary presenting complaint.

Q: Which of the following statements about radical hysterectomy in stage Ib cervical cancer compared to radiotherapy is false?

It is less complicated than radiotherapy.. ***It is less complicated than radiotherapy.*** - Radical hysterectomy is a **major surgical procedure** with potential complications like **hemorrhage**, infection, **ureteral injury**, and **lymphedema**, which can be significant and life-altering. - Radiotherapy, while having its own set of side effects (e.g., **vaginal stenosis**, bladder/rectal irritation), typically avoids the acute surgical risks and recovery period associated with extensive surgery. *Chance of recurrence is lower with radical hysterectomy.* - For early-stage cervical cancer (Ib1/Ib2), both **radical hysterectomy** and **radiotherapy** provide **comparable outcomes** in terms of recurrence rates. - The choice between therapies often depends on patient factors, surgeon expertise, and pathological findings, but neither consistently demonstrates a significantly lower recurrence rate over the other in large cohorts. *Ovarian function can be preserved.* - In younger patients undergoing **radical hysterectomy**, it is often possible to **preserve the ovaries** by transplanting them or avoiding their removal if not directly involved, thus maintaining **endocrine function**. - **Pelvic radiotherapy**, in contrast, invariably leads to **ovarian radiation** and subsequent **ovarian failure** and menopause. *Chance of survival is higher with radical hysterectomy.* - For early-stage cervical cancer (Ib), **overall survival rates** are generally **equivalent** between radical hysterectomy and primary radiotherapy. - Meta-analyses and large retrospective studies have shown **similar 5-year survival rates** for both treatment modalities when applied appropriately to well-selected patients.

Q: Fluorescein angiography is used to examine -

Retinal vasculature. ***Retinal vasculature*** - **Fluorescein angiography** involves injecting fluorescein dye into a vein and taking rapid photographs of the retina as the dye perfuses, allowing for detailed visualization of the **retinal blood vessels**. - This technique is crucial for diagnosing and monitoring conditions like **diabetic retinopathy**, **macular degeneration**, and **retinal vascular occlusions** by identifying leaks, non-perfusion areas, and abnormal vessel growth. *Ciliary vasculature* - The **ciliary body vasculature** is not directly visualized by standard fluorescein angiography as it is located anterior to the retina within the uveal tract. - While some dye may perfuse the ciliary body, the primary imaging target and diagnostic utility of fluorescein angiography are the **retinal and choroidal circulations**. *Corneal vasculature* - The normal **cornea is avascular**, meaning it does not contain blood vessels. - **Corneal neovascularization** (new vessel growth) can occur due to pathology, but fluorescein angiography is not the primary or most suitable technique for assessing corneal vessels, which are more readily visible with slit-lamp biomicroscopy. *Conjunctival vasculature* - The **conjunctiva** contains numerous small vessels, but these are superficial and can be directly observed with a slit lamp or even the naked eye. - Fluorescein angiography is an invasive procedure with a higher spatial resolution designed for deeper, more intricate vascular networks like those in the retina, making it overkill and inappropriate for routine assessment of the **conjunctival vasculature**.

Q: What is the most common structural deformity associated with transient synovitis of the hip?

None of the options. ***None of the options:*** - Transient synovitis of the hip is an inflammatory condition that does not inherently cause a **structural deformity** of the hip joint. - While it causes pain and limited range of motion, these are functional rather than structural changes, and the hip joint's **anatomical structure remains intact**. *Abduction* - Abduction is a **movement**, not a structural deformity. Although the hip may be held in a position of slight abduction to relieve pain, this is a postural adaptation, not a permanent structural change. - Hip abduction contractures can occur in various conditions (e.g., neuromuscular disorders) but are not characteristic of transient synovitis. *Flexion* - Similar to abduction, flexion is a **movement**, not a structural deformity. Patients with transient synovitis often hold the hip in a flexed position (along with abduction and external rotation) for comfort to minimize pressure within the joint capsule. - A fixed flexion deformity can be seen in other conditions like septic arthritis or Legg-Calvé-Perthes disease, but not typically in transient synovitis. *External rotation* - External rotation is also a **movement**, not a structural deformity. Patients may adopt an externally rotated position of the leg to ease pain and reduce intracapsular pressure. - While certain conditions can cause a fixed external rotation (e.g., slipped capital femoral epiphysis), transient synovitis does not lead to this type of structural change.

Q: What is a contraindication for ECT?

Cerebral aneurysm. ***Cerebral aneurysm*** * A **cerebral aneurysm** is considered a **relative contraindication** for electroconvulsive therapy (ECT) due to the increased risk of rupture from the transient, but significant, rise in **blood pressure** and **intracranial pressure** during the procedure. * The cardiovascular stress induced by the seizure can worsen pre-existing vascular pathologies in the brain, making it a high-risk condition. *Arrhythmia* * While various cardiac conditions require careful monitoring during ECT, **arrhythmias** are generally not an absolute contraindication. * Patients can often undergo ECT with proper **cardiac monitoring** and **pharmacological management** to control the heart rhythm during the procedure. *Epilepsy* * **Epilepsy** is not a contraindication for ECT; in fact, ECT *artificially induces a seizure* to achieve therapeutic effects. * The presence of epilepsy primarily impacts the choice of **anticonvulsant medications** and the need for potentially higher seizure thresholds, but it does not preclude ECT. *HIV* * **HIV infection** itself is not a contraindication for ECT. * ECT can be safely administered to HIV-positive individuals, with consideration given to the patient's overall **physical health**, **medication interactions**, and any co-morbid opportunistic infections.

Q: In which condition is psychosurgery considered as a last resort treatment?

Severe Obsessive-Compulsive Disorder. ***Severe Obsessive-Compulsive Disorder*** - Psychosurgery (e.g., **anterior cingulotomy**, **capsulotomy**) is considered for individuals with **severe, refractory OCD** who have not responded to conventional treatments. - This intervention aims to disrupt specific neural circuits implicated in OCD, such as the **corticostriatothalamocortical (CSTC) loop**. *Severe Generalized Anxiety Disorder* - While GAD can be debilitating, standard treatments like **psychotherapy (CBT)** and **pharmacotherapy (SSRIs, SNRIs)** are generally effective. - Psychosurgery is not typically considered for GAD, as less invasive and established treatments carry significantly lower risks. *Severe Depression* - For severe, treatment-resistant depression, **electroconvulsive therapy (ECT)** and **transcranial magnetic stimulation (TMS)** are more common and established interventions. - Psychosurgery is rarely, if ever, used for severe depression due to ethical concerns and the availability of less invasive options. *Severe Phobia* - Severe phobias primarily respond to **exposure therapy** and **cognitive behavioral therapy (CBT)**. - These therapies directly target the learned fear response and are highly effective without the need for invasive procedures.

Q: All are required to diagnose major depression except?

Nihilistic ideas. ***Nihilistic ideas*** - While nihilistic ideas (e.g., belief that life is meaningless or that nothing matters) can occur in severe depression, they are **not a mandatory diagnostic criterion** for major depressive disorder (MDD). - The diagnosis of MDD requires a specific number of core symptoms, and nihilistic ideation is not listed as one of them in diagnostic manuals like the DSM-5. *Depressed mood* - A **depressed mood** for most of the day, nearly every day, is one of the two **cardinal symptoms** required for a diagnosis of major depressive disorder. - The other cardinal symptom is anhedonia (loss of interest or pleasure). *Insomnia* - **Insomnia** (difficulty falling or staying asleep) or hypersomnia (sleeping excessively) is a common neurovegetative symptom of major depressive disorder and is one of the **nine diagnostic criteria**. - At least 5 of these 9 criteria must be present for a diagnosis, including at least one of the two cardinal symptoms. *Decreased concentration* - **Diminished ability to think or concentrate**, or indecisiveness, is another of the **nine diagnostic criteria** for major depressive disorder. - This cognitive symptom highlights the impact of depression on mental function beyond mood.

Question 1

What is the definition of conscious sedation?

Accepted Answer

Sedation with ability to respond to verbal commands

Answer

CNS depression with unconsciousness

Answer

Sedation with inability to respond to verbal commands

Answer

None of the options

Question 2

Which of the following drugs is effective in the treatment of pityriasis versicolor?

Accepted Answer

Ketoconazole

Answer

Metronidazole

Answer

Griseofulvin

Answer

Chloroquine

Question 3

In a patient with heart disease, which condition is most commonly associated with left atrial enlargement?

Accepted Answer

Mitral stenosis

Answer

Tricuspid regurgitation

Answer

AR

Answer

None of the options

Question 4

Most common presentation of cervical cancer is -

Accepted Answer

Abnormal vaginal bleeding

Answer

Pelvic pain

Answer

Pain during intercourse

Answer

Unusual vaginal discharge

Question 5

Which of the following statements about radical hysterectomy in stage Ib cervical cancer compared to radiotherapy is false?

Accepted Answer

It is less complicated than radiotherapy.

Answer

Chance of recurrence is lower with radical hysterectomy.

Answer

Ovarian function can be preserved.

Answer

Chance of survival is higher with radical hysterectomy.

Question 6

Fluorescein angiography is used to examine -

Accepted Answer

Retinal vasculature

Answer

Ciliary vasculature

Answer

Corneal vasculature

Answer

Conjunctival vasculature

Question 7

What is the most common structural deformity associated with transient synovitis of the hip?

Accepted Answer

None of the options

Answer

Abduction

Answer

Flexion

Answer

External rotation

Question 8

What is a contraindication for ECT?

Accepted Answer

Cerebral aneurysm

Answer

Epilepsy

Answer

HIV

Answer

Arrhythmia

Question 9

In which condition is psychosurgery considered as a last resort treatment?

Accepted Answer

Severe Obsessive-Compulsive Disorder

Answer

Severe Generalized Anxiety Disorder

Answer

Severe Depression

Answer

Severe Phobia

Question 10

All are required to diagnose major depression except?

Accepted Answer

Nihilistic ideas

Answer

Depressed mood

Answer

Decreased concentration

Answer

Insomnia

NEET-PG 2013

Anesthesiology

Dermatology

Internal Medicine

Obstetrics and Gynecology

Ophthalmology

Orthopaedics

Psychiatry