NEET-PG 2013 Practice Questions

Q: Ganser syndrome is classified under which of the following disorders?

Dissociative disorder. ***Dissociative disorder*** - Ganser syndrome is characterized by a "passing-off" behavior, where the individual gives **approximate or nonsensical answers** to simple questions, often associated with other dissociative symptoms. - While historically difficult to classify, contemporary understanding places it within the spectrum of dissociative disorders due to its features of an altered state of consciousness and a detachment from reality. *OCD* - **Obsessive-compulsive disorder (OCD)** involves recurrent, intrusive thoughts (obsessions) and repetitive behaviors or mental acts (compulsions). - Ganser syndrome does not typically present with the classic symptom profile of obsessions and compulsions. *Conversion disorder* - **Conversion disorder** involves neurological symptoms (e.g., paralysis, blindness, seizures) that are not consistent with neurological disease and are often preceded by psychological stress. - While both involve psychological factors, Ganser syndrome is distinct in its presentation of "answers" that are close but incorrect, rather than physical symptoms. *Schizoid personality disorder* - **Schizoid personality disorder** is characterized by a pervasive pattern of detachment from social relationships and a restricted range of expression of emotions in interpersonal settings. - This disorder primarily affects social functioning and emotional expression, which is different from the specific cognitive and behavioral pattern seen in Ganser syndrome.

Q: Which of the following statements is NOT true about type 1 schizophrenia?

It has a poor prognosis.. ***It has a poor prognosis.*** - This statement is **NOT true** about type 1 schizophrenia, making it the correct answer to this question. - Type 1 schizophrenia is generally associated with a **better prognosis** and good response to antipsychotic medication. - It is characterized by the prominence of **positive symptoms**, which tend to be more responsive to treatment. *It is an acute illness.* - This statement is **TRUE** about type 1 schizophrenia, so it is not the answer. - Type 1 schizophrenia is often characterized by an **acute onset** of symptoms, particularly positive symptoms. - This acute presentation differentiates it from type 2, which typically has a more insidious onset. *Intellect is usually maintained.* - This statement is **TRUE** about type 1 schizophrenia, so it is not the answer. - In type 1 schizophrenia, **cognitive function**, including intellect, is usually better preserved compared to type 2 schizophrenia. - While some cognitive deficits may occur, they are generally less severe and less pervasive than in type 2. *It is characterized by negative symptoms.* - This statement is **FALSE** about type 1 schizophrenia, but it is not the best answer because the prognosis statement is more definitively incorrect. - Type 1 schizophrenia is primarily characterized by the predominance of **positive symptoms**, such as hallucinations, delusions, and disorganized thought. - **Negative symptoms** (e.g., apathy, anhedonia, alogia, blunted affect) are the hallmark of type 2 schizophrenia.

Q: In stupor catatonia, all are seen except -

Agitation. ***Agitation*** - **Stuporous catatonia** is characterized by a significant reduction or absence of motor activity and responsiveness, making **agitation**—increased motor activity—an unlikely feature. - In such a state, the patient is typically rigid, immobile, and unresponsive to external stimuli, which is the antithesis of agitation. *Catalepsy* - **Catalepsy** refers to a trance-like state with a loss of voluntary motion and active posturing, where the limbs maintain any position in which they are placed (waxy flexibility). - This is a hallmark feature of **catatonic stupor**, indicating a profound disturbance in motor control. *Mutism* - **Mutism** is the absence or profound reduction of speech, which is a common and defining feature of **catatonic stupor**. - Patients in a stuporous state typically do not speak or respond verbally to questions or commands. *Akinesia* - **Akinesia** is the absence of movement, or pronounced difficulty in initiating voluntary movements, which is a key component of **catatonic stupor**. - Patients exhibit severe motor retardation, often appearing frozen or rigid.

Q: What is the most likely neurochemical change associated with schizophrenia?

Increased dopaminergic activity. ***Increased dopaminergic activity*** - The **dopamine hypothesis** of schizophrenia posits that the positive symptoms (hallucinations, delusions) are mainly due to **hyperactivity of dopamine D2 receptors** in the mesolimbic pathway. - Most **antipsychotic medications** work by blocking these D2 receptors, reducing dopaminergic transmission and alleviating symptoms. *Increased GABA activity* - **GABA (gamma-aminobutyric acid)** is the primary inhibitory neurotransmitter in the brain; *decreased* GABAergic activity has been implicated in schizophrenia, not increased. - A reduction in GABAergic interneurons can lead to **disinhibition** and contribute to cognitive deficits and positive symptoms. *Decreased dopaminergic activity* - While *decreased* dopamine activity in the **mesocortical pathway** (leading to the prefrontal cortex) is associated with the negative symptoms (e.g., avolition, anhedonia) and cognitive deficits of schizophrenia, the *primary* neurochemical change linked to the characteristic psychotic symptoms is an *increase* in mesolimbic dopamine. - Therefore, considering the overall presentation, **increased dopamine** is the most likely and direct answer. *Decreased norepinephrine activity* - Although **norepinephrine dysregulation** has been observed in schizophrenia, it is not considered the primary neurochemical change. - Changes in norepinephrine are often secondary or contribute to specific symptom clusters like **attention deficits** or mood disturbances rather than the core psychotic features.

Q: In which socioeconomic strata is schizophrenia most commonly observed?

Low. ***Low*** - Epidemiological studies consistently show a **higher prevalence of schizophrenia** in individuals from **lower socioeconomic strata**. - This association is explained by the "**social drift**" hypothesis, where individuals with schizophrenia experience a decline in social class due to the chronic and disabling nature of the illness, or the "**social causation**" hypothesis, which posits that adverse social conditions contribute to the development of the disorder. *Middle* - While individuals from all socioeconomic backgrounds can develop schizophrenia, it is **less common** compared to the lowest strata. - The middle socioeconomic group generally experiences **better access to resources** and support systems, which may mitigate some risk factors. *Upper* - Schizophrenia is **least common** in the upper socioeconomic strata. - Individuals in this group typically have **greater financial stability**, better living conditions, and access to high-quality healthcare, which might protect against environmental stressors. *Upper middle* - Similar to the middle and upper strata, the upper-middle class experiences a **lower prevalence of schizophrenia** compared to the low socioeconomic group. - This group often benefits from **good educational opportunities** and stable employment, reducing some of the psychosocial stressors associated with the disorder.

Q: Which of the following is considered a poor prognostic factor for schizophrenia?

Early onset. ***Early onset*** - An **earlier age of onset** (e.g., childhood or early adolescence) for schizophrenia is consistently associated with a **worse long-term prognosis**, including more severe symptoms, greater functional impairment, and a lower likelihood of full recovery. - This is thought to be due to the greater developmental disruption caused by the illness when it begins at a younger age. *Presence of depression* - While depression is common in schizophrenia, it is generally considered to be a **treatable co-occurring condition** rather than a primary poor prognostic factor for the core psychotic disorder itself. - Effective treatment for depression can actually **improve overall quality of life** and adherence to antipsychotic medication. *Presence of stressor* - The presence of a significant psychosocial stressor at the onset of schizophrenia is often associated with a **better prognosis**, as it suggests a more reactive and potentially remitting course. - This indicates that the illness might be more environmentally triggered and less intrinsically severe. *Female sex* - **Female sex** is typically associated with a **somewhat better prognosis** in schizophrenia, with a later age of onset and potentially less severe symptoms compared to males. - This may be influenced by hormonal factors and differences in social support networks.

Q: Which of the following is considered a poor prognostic factor for schizophrenia?

Poor premorbid adjustment. **Poor premorbid adjustment** - **Poor premorbid adjustment**, indicated by difficulties in social, academic, or occupational functioning before the onset of psychosis, is a consistent predictor of a worse outcome in schizophrenia. - This suggests a more pervasive and entrenched neurodevelopmental vulnerability impacting the individual's ability to cope and integrate socially. *Blunted affect (negative symptom)* - While **blunted affect** is a negative symptom often associated with poorer outcomes than positive symptoms, it is typically considered a *symptom* of the illness rather than a primary prognostic *factor* like premorbid adjustment. - Its presence contributes to disability, but it is not as strong an independent prognostic indicator as the life trajectory prior to illness onset. *Male sex (generally poorer prognosis)* - **Male sex** is generally associated with an **earlier age of onset** and often a **more severe course** of schizophrenia. - However, compared to significant functional impairment before disease onset, it is not as strong an individual predictor of overall long-term prognosis. *Presence of depression (often associated with better outcomes)* - The **presence of depressive symptoms** in schizophrenia is often associated with a **better prognosis**. - This is because depressive features can sometimes indicate a more preserved capacity for emotional experience and insight, which can align with higher functioning.

Q: Which of the following is not considered a core diagnostic criterion for schizophrenia according to DSM-5?

Social withdrawal. ***Social withdrawal*** - While **social withdrawal** is a common clinical feature and often reflects negative symptoms in schizophrenia, it is **not specifically listed** as one of the **five core diagnostic criteria (Criterion A)** in DSM-5. - The five core symptom domains are: delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, and negative symptoms (diminished emotional expression or avolition). - Social withdrawal may be a manifestation of negative symptoms or part of **social/occupational dysfunction (Criterion B)**, but it is not itself a distinct core diagnostic criterion. *Catatonia* - **Catatonic behavior** (such as stupor, catalepsy, waxy flexibility, posturing, or mutism) is explicitly included as part of the **fourth core diagnostic criterion**: "Grossly disorganized or catatonic behavior." - This makes it one of the five primary symptom domains in **Criterion A** of DSM-5. - Note: "Catatonia" as a **specifier** (requiring 3+ out of 12 symptoms) is different from catatonic behavior as a core symptom. *Hallucinations* - **Hallucinations** (most commonly auditory, but can be visual, tactile, olfactory, or gustatory) are the **second core diagnostic criterion** in DSM-5. - At least **two of the five core symptoms** must be present, and hallucinations fulfill this requirement as a key **positive symptom**. *Disorganized speech* - **Disorganized speech** (formal thought disorder) is the **third core diagnostic criterion** for schizophrenia. - Characterized by **derailment, tangentiality, incoherence, or loose associations**, it reflects significant disruption in organized thinking and communication.

Q: Which of the following is NOT considered one of Bleuler's fundamental symptoms of schizophrenia?

Delusions. ***Delusions*** - **Delusions** are considered a **first-rank symptom** of schizophrenia according to Schneider, but not one of Bleuler's fundamental "4 A's". - Bleuler classified delusions as **accessory symptoms**, which are variable and not always present, unlike fundamental symptoms. *Loosening of associations* - This is one of Bleuler's **"4 A's"**, representing a disturbance in the logical flow of thought, leading to incoherent speech and fractured thinking. - Bleuler saw this as a core cognitive dysfunction in schizophrenia. *Affect disturbances* - This refers to **inappropriate affect** (e.g., laughing at a funeral) or **blunted/flattened affect**, which is another of Bleuler's "4 A's." - It signifies a disruption in the normal experience and expression of emotions. *Autism* - Bleuler's term **"autism"** (or autismus) refers to a pathological self-preoccupation, withdrawal from social interaction, and an immersion in one's own internal world. - This is also one of Bleuler's **"4 A's"**, highlighting a foundational disturbance in social engagement.

Q: Which of the following is NOT a feature of neurosis?

Personality disturbances. ***Personality disturbances*** - While neurosis can cause significant distress and impact functioning, it does not typically involve **fundamental alterations in personality structure or identity**. - **Personality disorders**, not neuroses, are characterized by deeply ingrained, inflexible, and maladaptive patterns of perceiving, thinking, and behaving that deviate markedly from cultural expectations. *Symptoms cause subjective distress* - A core characteristic of neurosis is that the individual experiences significant **emotional suffering** and discomfort due to their symptoms, such as anxiety, phobias, or obsessions. - This **subjective distress** is often a primary motivator for seeking treatment. *Contact with reality preserved* - Individuals with neurosis maintain their ability to **distinguish between internal experiences and external reality**, unlike in psychosis where this distinction is lost. - They may understand that their fears or anxieties are irrational, but they are unable to control them. *Insight is maintained* - People with neurosis generally have some level of **awareness** that they have a problem or that their symptoms are unreasonable or excessive. - This **insight** allows them to recognize the need for help and engage in therapeutic processes.

Question 1

Ganser syndrome is classified under which of the following disorders?

Accepted Answer

Dissociative disorder

Answer

OCD

Answer

Conversion disorder

Answer

Schizoid personality disorder

Question 2

Which of the following statements is NOT true about type 1 schizophrenia?

Accepted Answer

It has a poor prognosis.

Answer

Intellect is usually maintained.

Answer

It is an acute illness.

Answer

It is characterized by negative symptoms.

Question 3

In stupor catatonia, all are seen except -

Accepted Answer

Agitation

Answer

Mutism

Answer

Akinesia

Answer

Catalepsy

Question 4

What is the most likely neurochemical change associated with schizophrenia?

Accepted Answer

Increased dopaminergic activity

Answer

Increased GABA activity

Answer

Decreased dopaminergic activity

Answer

Decreased norepinephrine activity

Question 5

In which socioeconomic strata is schizophrenia most commonly observed?

Accepted Answer

Low

Answer

Middle

Answer

Upper

Answer

Upper middle

Question 6

Which of the following is considered a poor prognostic factor for schizophrenia?

Accepted Answer

Early onset

Answer

Presence of depression

Answer

Presence of stressor

Answer

Female sex

Question 7

Which of the following is considered a poor prognostic factor for schizophrenia?

Accepted Answer

Poor premorbid adjustment

Answer

Male sex

Answer

Presence of depression

Answer

Blunted affect

Question 8

Which of the following is not considered a core diagnostic criterion for schizophrenia according to DSM-5?

Accepted Answer

Social withdrawal

Answer

Catatonia

Answer

Hallucinations

Answer

Disorganized speech

Question 9

Which of the following is NOT considered one of Bleuler's fundamental symptoms of schizophrenia?

Accepted Answer

Delusions

Answer

Loosening of associations

Answer

Affect disturbances

Answer

Autism

Question 10

Which of the following is NOT a feature of neurosis?

Accepted Answer

Personality disturbances

Answer

Symptoms cause subjective distress

Answer

Contact with reality preserved

Answer

Insight is maintained

NEET-PG 2013

Psychiatry