Antivirals — Flashcards

Which two antiviral drugs directly inhibit DNA polymerase?_____

Do NRTIs require phosphorylation to be activated?_____

Do NNRTIs compete with nucleotides for binding to reverse transcriptase?_____

Which NRTI is associated with myelosuppresion?_____

_____ is the prodrug form of Ganciclovir that has better oral bioavailability.

Foscarnet can cause _____ due to electrolyte disturbances

Which ion imbalances are associated with Foscarnet administration?_____

Oseltamivir / zanamivir also prevent influenza by impairing viral penetration of _____ that overlie the respiratory epithelium

NRTIs lack a 3 hydroxyl group, causing strand termination when binding to _____

Interferon Beta protects the _____ Barrier by preventing extravasation of lymphocytes