Antivirals — Flashcards

Flashcard 101: What is the treatment of serious HSV and VZV infections? _____

Answer: IV acyclovir

Flashcard 102: What drugs are used to prevent breakouts of Herpes Simplex Virus? _____

Answer: Acyclovir; Valacyclovir

Flashcard 103: Adverse effects associated with sofosbuvir include _____ and _____

Answer: fatigue

Extra: Sketchy Pharmacology: GI (Hepatitis)

Flashcard 104: Nevirapine is associated with _____ of cytochrome p450 enzymes

Answer: induction

Flashcard 105: Integrase inhibitors will inhibit HIV _____ integration into the host cell genome, preventing _____ production

Answer: dsDNA

Flashcard 106: NNRTIs are _____ inhibitors of the HIV Reverse Transcriptase

Answer: non-competitive

Flashcard 107: NRTIs are nucleosides or nucleotides that have an absent _____

Answer: 3' hydroxyl group

Flashcard 108: Do NNRTI's need to be phosphorylated to be active? _____

Answer: No

Flashcard 109: _____ is a(n) CCR5 inhibitor that inhibits HIV entrance into macrophages early in the disease course

Answer: Maraviroc

Flashcard 110: Palivizumab is a monoclonal antibody against the _____ of RSV

Answer: fusion (F) protein