Antivirals US Medical PG Flashcards - Medical Study Cards
Master Antivirals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antivirals Flashcard Deck - 10 Cards
Flashcard 91: Patients taking Foscarnet can experience various _____ abnormalities
Answer: electrolyte
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 92: Which NRTIs are particularly associated with peripheral neuropathy?
_____
Answer: Didanosine (ddI), Stavudine (d4T), and Zalcitabine (ddC)
Extra: The "d-drugs" (Didanosine, Stavudine, Zalcitabine) are associated with peripheral neuropathy and pancreatitis due to mitochondrial toxicity. They are generally not used in combination with one another due to additive toxicity.
Flashcard 93: Which two anti-influenza drugs inhibit the M2 channels?
_____
Answer: Amantadine; Rimantadine
Extra:
Watch Influenzavirus (Orthomyxoviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-negative-sense-influenzavirus-orthomyxoviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 94: What is the treatment for Acyclovir-resistant HSV?
_____
Answer: Foscarnet or Cidofovir
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 95: Pyrimidine nucleoside analogs (e.g., cytarabine and gemcitabine) work by inhibiting _____.
Answer: DNA polymerase
Extra: Cytarabine (Ara-C) is primarily used for hematologic malignancies (e.g., AML, lymphomas). Gemcitabine is used for solid tumors (e.g., pancreatic, lung, bladder cancers).
Flashcard 96: Acyclovir, Famciclovir, Valacyclovir, Ganciclovir, and Valganciclovir target which process in the viral life cycle?\n_____
Answer: Viral DNA synthesis (DNA polymerase)
Extra: Acyclovir, Valacyclovir, and Famciclovir require viral thymidine kinase for initial phosphorylation. Ganciclovir and Valganciclovir require viral UL97 kinase (in CMV). These drugs are nucleoside analogs that act as chain terminators once incorporated into viral DNA.
Flashcard 97: The MMR vaccine should be avoided in _____ and _____ patients
Answer: pregnant
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/vaccinations?index=4]
https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki
Flashcard 98: What is the method of administration of the sabin vaccine?
_____
Answer: Orally
Extra:
Watch Poliovirus (PicoRNAviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-positive-sense-poliovirus-picornaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/vaccinations?index=4]
https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki
Flashcard 99: Which type of HAART drug is Ritonavir?
_____
Answer: Protease inhibitor
Extra:
Watch Protease inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-protease-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 100: Ganciclovir is converted to ganciclovir monophosphate by virus-encoded kinases via the _____ gene
Answer: UL-97
Extra:
Watch Ganciclovir, valganciclovir, foscarnet, cidofovir [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-other-ganciclovir-valganciclovir-foscarnet-cidofovir?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
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