Antibiotics — Flashcards

Flashcard 901: Macrolides can be used to treat Pertussis as long as it is still in the _____ phase

Answer: catarrhal

Flashcard 902: Is Vancomycin susceptible to beta-lactamases?

Answer: No (it is not a beta-lactam)

Extra: Vancomycin is a glycopeptide antibiotic. Since it lacks a beta-lactam ring, it is not susceptible to hydrolysis by beta-lactamases. It inhibits cell wall synthesis by binding to the D-Ala-D-Ala terminus of peptidoglycan precursors.

Flashcard 903: What class of drugs does doxorubicin belong to?_____

Answer: Anthracyclines (antitumor antibiotics)

Flashcard 904: _____ is a protein synthesis inhibitor that binds to the 50s subunit and can be used in the treatment of chlamydia.

Answer: Azithromycin

Flashcard 905: What is one specific gram negative rod monobactams treat?_____

Answer: Pseudomonas

Flashcard 906: When taken during early pregnancy, Trimethoprim can cause the baby to develop _____

Answer: neural tube defects

Flashcard 907: Which antibiotics can result in acute cholestatic hepatitis?_____

Answer: Macrolides (-thromycin)

Flashcard 908: What is the treatment for Proteus mirabilis pyelonephritis?_____

Answer: Fluoroquinolones

Flashcard 909: _____ are a class of protein synthesis inhibiting antibiotics that are effective against intracellular organisms by virtue of their ability to accumulate intracellularly.

Answer: Tetracyclines

Flashcard 910: Tetracyclines are bacterio-_____

Answer: static