Antibiotics — Flashcards

Which antibiotic binds the 30S ribosomal subunit, irreversibly inhibiting formation of the initiation complex?_____

Pyrazinamide is an antibiotic only used to treat _____

Which β-lactam antibiotics result in increased nephrotoxicity when combined with aminoglycosides?

What lipopeptide can be used to treat VRE (vancomycin resistant enterococcus)?_____

90% of Vancomycin is excreted by _____ filtration

Which generations of cephalosporins have the largest spectrum of activity?_____

Rifabutin _____ cytochrome p450 (induces or inhibits)

Macrolides are _____ of CYP-450

What antibiotics (2) are used to treat hepatic encephalopathy? _____

Aztreonam is especially useful for patients with _____-insufficiency (and therefore can't tolerate aminoglycosides)