Antibiotics — Flashcards

Flashcard 891: Which antibiotic is used to treat C. difficile (pseudomembranous colitis) that is unresponsive to Metronidazole?_____

Answer: Oral Vancomycin

Flashcard 892: What is the drug of choice for all stages of syphilis?

Answer: Penicillin G

Extra: The formulation and route of Penicillin G depend on the stage of syphilis: - **Primary, Secondary, and Latent syphilis**: Benzathine Penicillin G (intramuscular). - **Neurosyphilis**: Aqueous Crystalline Penicillin G (intravenous). *Note: Penicillin G remains the drug of choice for all stages, but Benzathine Penicillin G specifically is contraindicated for neurosyphilis due to poor CSF penetration.*

Flashcard 893: Treatment of MSSA Staph aureus right-sided endocarditis_____

Answer: Anti-staph penicillins (nafcillin, oxacillin, dicloxacillin, methicillin)

Flashcard 894: Clostridium difficile can be treated with metronidazole, vancomycin, or _____

Answer: fidaxomicin

Flashcard 895: What class of drugs does doxorubicin belong to?_____

Answer: Anthracyclines (antitumor antibiotics)

Flashcard 896: What antibiotic can increase risk for serotonin syndrome? _____

Answer: Linezolid

Flashcard 897: _____ are a class of protein synthesis inhibiting antibiotics that are effective against intracellular organisms by virtue of their ability to accumulate intracellularly.

Answer: Tetracyclines

Flashcard 898: Which antibiotics can result in acute cholestatic hepatitis?_____

Answer: Macrolides (-thromycin)

Flashcard 899: Which class of antibiotics are teratogenic, causing deafness in newborns?_____

Answer: Aminoglycosides

Flashcard 900: Rifabutin _____ cytochrome p450 (induces or inhibits)

Answer: induces