Antibiotics — Flashcards

Flashcard 721: Which beta-lactam antibiotic lowers the seizure threshold?_____

Answer: Imipenem

Flashcard 722: What is the treatment for assumed-methicillin resistant Staphylococcus epidermidis?_____

Answer: Vancomycin

Flashcard 723: Which drug elimination is characterized by a constant fraction of drug eliminated per unit time?_____

Answer: First-order elimination

Flashcard 724: Which antibiotic causes the misreading of mRNA and inhibition of translation?_____

Answer: Aminoglycosides

Flashcard 725: Mupirocin is a topical antibiotic that works by inhibiting _____

Answer: isoleucine t-RNA synthetase

Flashcard 726: What is the treatment for Pasteurella multocida?_____

Answer: Penicillin

Flashcard 727: Which anti-microbial class is Aztreonam particularly synergistic with?_____

Answer: Aminoglycosides

Flashcard 728: Carbapenems treat meningitis and pneumonia caused by _____ pathogens

Answer: gram negative

Flashcard 729: Clindamycin has activity against methicillin-resistant _____

Answer: Staph aureus

Flashcard 730: What step of bacterial protein synthesis is inhibited by **Clindamycin**?

Answer: Inhibits **translocation** by binding to the **50S** ribosomal subunit.

Extra: Clindamycin's mechanism is similar to macrolides (e.g., erythromycin). It binds to the 50S subunit, preventing the movement of the ribosome along the mRNA (translocation).