Antibiotics — Flashcards

Flashcard 591: Cephalosporins: susceptibility to β-lactamases (penicillinases)

Answer: Relatively resistant (less susceptible than penicillins)

Extra: Cephalosporins are β-lactam antibiotics that are structurally more resistant to many β-lactamases (specifically penicillinases) compared to penicillins. However, they are still susceptible to specific enzymes like cephalosporinases and extended-spectrum β-lactamases (ESBLs).

Flashcard 592: What cephalosporin can bind the altered PBPs of MRSA? _____

Answer: Ceftaroline

Flashcard 593: Aminoglycosides are actively transported into the cell via an _____-dependent process

Answer: oxygen

Flashcard 594: DOC for gonorrhea_____

Answer: Ceftriaxone

Flashcard 595: Which bacterial ribosomal subunit is targeted by Chloramphenicol?_____

Answer: 50S

Flashcard 596: Isoniazid therapy indirectly decreases vitamin _____ by decreasing levels of vitamin B6

Answer: B3

Flashcard 597: _____ is an aminopenicillin that can be used to treat (non-vancomycin resistant) Enterococcus infection (E. faecalis, E. faecium).

Answer: Ampicillin

Flashcard 598: Penicillin binds to PBP transpeptidases by mimicking the _____ sequence of peptidoglycan

Answer: D-ala-D-ala

Flashcard 599: Vancomycin is bacterio-_____

Answer: cidal

Flashcard 600: The metabolic acidosis associated with Isoniazid use has a(n) _____ anion gap (normal or elevated)

Answer: elevated