Antibiotics — Flashcards

_____ are bacterial enzymes involved in cell wall synthesis that are the target site for beta-lactam antibiotics.

Penicillin binds to PBP transpeptidases by mimicking the _____ sequence of peptidoglycan

Which antibiotics bind the 23S rRNA of the 50S ribosomal subunit of bacteria?_____

Resistance to Tetracyclines includes bacterial production of _____ pumps

DOC for gonorrhea_____

Phase _____ of clinical trials detects rare or long-term adverse effects, and drug interactions

What drug is an inhibitor of both prokaryotic AND eukaryotic RNA polymerase? _____

Isoniazid use can result in metabolic _____ (acidosis or alkalosis)

Isoniazid therapy indirectly decreases vitamin _____ by decreasing levels of vitamin B6

What cephalosporins are first line for empiric treatment of meningitis?_____