Antibiotics — Flashcards

Flashcard 281: Sulfonamides can cause sloughing of skin at the dermal-epidermal junction, a condition known as _____.

Answer: Stevens-Johnson syndrome

Extra: Sulfonamides are a frequent trigger for Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). These hypersensitivity reactions are characterized by keratinocyte necrosis and detachment of the epidermis from the dermis at the dermal-epidermal junction. SJS is typically defined as involving <10% body surface area (BSA), whereas TEN involves >30% BSA.

Flashcard 282: TMP-SMX can be used to treat acute _____ in men

Answer: prostatitis

Extra:   Watch Trimethoprim/Sulfamethoxazole [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-trimethoprimsulfamethoxazole?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki 

Flashcard 283: To be active, **Imipenem** must be administered with an inhibitor of _____, an inactivating enzyme located in the Kidney

Answer: Dehydropeptidase I

Flashcard 284: Which antibiotics can result in neuromuscular blockade? _____

Answer: Aminoglycosides

Extra:   Watch Aminoglycosides [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-aminoglycosides?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 285: Is Rifampin/Rifabutin indicated to treat both tuberculous and nontuberculous mycobacteria? _____

Answer: Yes

Extra:    https://onlinemeded.org/spa/microbiology/antimycobacterials/acquire?ref=anki 

Flashcard 286: Fluoroquinolones impact bacterial DNA genetics by inhibiting _____ and Topoisomerase IV.

Answer: DNA gyrase (Topoisomerase II)

Flashcard 287: Are Tetracyclines indicated for patients who are experiencing symptoms of Meningitis? _____

Answer: No

Extra:   https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 288: Which of the antitumor antibiotics can cause hyperpigmentation of skin? _____

Answer: Bleomycin

Extra:   Watch Bleomycin, doxorubicin, daunorubicin, actinomycin D [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-bleomycin-doxorubicin-daunorubicin-actinomycin-d?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki 

Flashcard 289: Patients on chronic _____ therapy should not be prescribed fluoroquinolones due to a significantly increased risk of tendon / cartilage damage

Answer: steroid

Extra:    https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 290: Daptomycin is a lipopeptide used to treat Multi Drug Resistant Gram-_____ infections

Answer: Positive Cocci

Extra:   https://onlinemeded.org?ref=anki