Molecular Genetics — Flashcards

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

Upregulation of _____ prevents chromosomal shortening and cell death in tumors

What type of probe is used to bind DNA/RNA when using a Southern/Northern blot? _____

Which tumor suppressor genes are associated with colon cancer?_____

If two linked genes have a recombination frequency of 15%, approximately how far apart are they?_____

What tumour suppressor gene does the E6 protein from Human Papillomavirus (HPV) bind to and inhibit?_____

In both Angelman syndrome and Prader-Willi syndrome, the most common abnormality is a gene _____

The most common CFTR gene mutation (cystic fibrosis) results in a misfolded protein that is retained in the _____

Which pyrimidine is found in RNA only?_____

Which purine is characterized by no amino group at the 12 o'clock position?_____