Molecular Genetics — Flashcards

What class of enzymes breaks down DNA in apoptosis?_____

Is achondroplasia typically seen in patients with homozygous or heterozygous mutations?_____

If two linked genes have a recombination frequency of 15%, approximately how far apart are they?_____

What tumour suppressor gene does the E6 protein from Human Papillomavirus (HPV) bind to and inhibit?_____

A _____ mutation occurs when a nucleotide substitution codes for a stop codon

What chromosome is cyclin D1 located on? _____

One feature of the genetic code is that it is _____: each codon specifies only 1 amino acid

Which protein from high-risk HPV binds to Rb (specifically p105-Rb)?_____

Upregulation of _____ prevents chromosomal shortening and cell death in tumors

Patients with kallmann syndrome most commonly have mutations in the _____ or FGFR-1 genes