Molecular Genetics — Flashcards

_____ is a lysosomal storage disease caused by splice site mutations.

What gene is defective in Menkes disease? _____

What type of probe is used to bind DNA/RNA when using a Southern/Northern blot? _____

Which tumor suppressor genes are associated with colon cancer?_____

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

What is the most common mode of inheritance of Alport syndrome? _____

Patients with kallmann syndrome most commonly have mutations in the _____ or FGFR-1 genes

One feature of the genetic code is that it is _____: each codon specifies only 1 amino acid

What tumour suppressor gene does the E6 protein from Human Papillomavirus (HPV) bind to and inhibit?_____

Which hemoglobin type migrates the least far from the negative electrode on electrophoresis? _____