Molecular Genetics — Flashcards

The most common CFTR gene mutation (cystic fibrosis) results in a misfolded protein that is retained in the _____

Which pyrimidine is found in RNA only?_____

What is the mode of inheritance of Tay-Sachs disease?_____

What type of oncogene is RET?_____

Mutations in CDK4 can cause melanoma due to a resultant _____ of the protein's activity

The G6PD isoform genes are located on the _____

If alleles at two loci are inherited equally as expected by chance, the loci are said to be in _____

What is the mode of inheritance of hypophosphatemic rickets (vitamin D-resistant rickets)? _____

Which pyrimidine is characterized by the presence of methyl groups, but no amino group at the 12 o'clock position?_____

Are the Bcl-2 related proteins Bcl-2 and Bcl-x pro- or anti-apoptotic? _____