Molecular Genetics US Medical PG Flashcards - Medical Study Cards
Master Molecular Genetics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Molecular Genetics Flashcard Deck - 10 Cards
Flashcard 331: What is the most common mechanism of chromosomal aneuploidy?
_____
Answer: Meiotic nondisjunction
Extra:
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 332: Sickled cells become _____ due to irreversible damage from persistent polymerization-depolymerization cycles, which exacerbates polymerization and sickling
Answer: stiff
Extra:
* persistent sickle shape -> potassium leakage -> cellular dehydration -> increased HbS concentration -> further polymerization and sickling
https://onlinemeded.org/spa/pediatrics/sickle-cell-disease/acquire?ref=anki
Flashcard 333: The intracellular receptors for steroid hormones, thyroid hormones, and vitamins A/D use _____ motifs to bind DNA.
Answer: zinc finger
Extra: Zinc finger motifs are the most common DNA-binding domain. Receptors for steroid hormones, thyroid hormones, and vitamins A/D (fat-soluble) belong to the nuclear receptor superfamily and act as transcription factors.
Flashcard 334: α-fetoprotein (AFP) is a protein that is normally made by the _____
Answer: fetus
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/high-yield-genetic-disorders?index=6]
https://onlinemeded.org?ref=anki
Flashcard 335: If a disease has a mitochondrial inheritance pattern, it can be inherited only from the _____
Answer: mother
Extra:
Watch Mitochondrial Inheritance Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-clinical-genetics/videos/medical-biochemistry-clinical-genetics-mitochondrial-diseases-mitochondrial-inheritance-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/basics-of-clinical-genetics?index=4]
https://onlinemeded.org/spa/genetics/modes-of-inheritance/acquire?ref=anki
Flashcard 336: A(n) _____ is a base plus a sugar (ribose or deoxyribose) plus phosphate
Answer: nucleoTide
Extra:
Watch Chromatin Structure [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-chromatin-structure?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=2]
https://onlinemeded.org?ref=anki
Flashcard 337: What sequence of nucleotides is repeated in Huntington disease?
_____
Answer: CAG
Extra:
Watch Creutzfeldt Jakob Disease, Parkinsons Disease & Huntingtons Disease [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-neurodegenerative-creutzfeldt-jakob-disease-parkinsons-disease-and-huntingtons-disease?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/high-yield-genetic-disorders?index=5]
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 338: Bcl2 is an anti-apoptotic molecule that sits on chromosome _____
Answer: 18
Extra:
https://onlinemeded.org/spa/inflammation-and-neoplasia/apoptosis/acquire?ref=anki
Flashcard 339: What cell cycle phase do DNA and histone synthesis occur?
_____
Answer: S phase
Extra:
Watch Cell Cycle [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-cell-biology/videos/medical-biochemistry-cell-biology-cell-cycle-and-division-cell-cycle?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=12]
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 340: Cyclin-Dependent Kinases are constitutive and are normally _____
Answer: inactive
Extra:
https://onlinemeded.org?ref=anki
Keywords: Molecular Genetics flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
