Molecular Genetics — Flashcards

Flashcard 211: What point mutations in the HFE gene are typically seen with primary hemochromatosis? _____ (more common) and H63D

Answer: C282Y

Extra: Atlas:

Flashcard 212: What chromosome is cyclin D1 located on? _____

Answer: Chromosome 11

Extra: Atlas: Other:

Flashcard 213: Once a steroid hormone has bound its receptor in the cytoplasm or nucleus, the hormone-receptor complex then _____

Answer: dimerizes

Flashcard 214: What is the mode of inheritance of G6PD deficiency? _____

Answer: X-linked recessive

Extra: Other:

Flashcard 215: DNA replication errors lead to _____ mutations

Answer: mismatch base

Flashcard 216: _____ is the normal differential expression of an allele depending on parental origin (e.g. only one allele is active)

Answer: Genetic imprinting

Flashcard 217: A(n) Southern blot is used to analyze _____

Answer: DNA

Flashcard 218: What is the function of the H1 class of histones? _____

Answer: Condense/link the nucleosomes together

Flashcard 219: Telomerase is a rare example where _____ activity occurs endogenously in humans

Answer: reverse transcriptase

Flashcard 220: How can enhancers be far away from the gene it regulates? _____

Answer: DNA will bend to bring enhancer to promoter