Molecular Genetics US Medical PG Flashcards - Medical Study Cards
Master Molecular Genetics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Molecular Genetics Flashcard Deck - 10 Cards
Flashcard 221: How can enhancers be far away from the gene it regulates?
_____
Answer: DNA will bend to bring enhancer to promoter
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=4]
https://onlinemeded.org?ref=anki
Flashcard 222: Where are estrogen receptors expressed (cell membrane, cytoplasm, nucleus)?
_____
Answer: Nucleus
Extra: Estrogen, progesterone, testosterone, T3/T4, and vitamin D receptors are located in the **nucleus**.
Glucocorticoid and mineralocorticoid receptors are located in the **cytoplasm** (and translocate to the nucleus upon ligand binding).
Flashcard 223: _____ is the production of a recombinant DNA molecule that is self-perpetuating
Answer: Cloning
Extra:
https://onlinemeded.org?ref=anki
Flashcard 224: Primary lactase deficiency occurs due to absence of the _____ allele
Answer: lactase-persistence
Extra:
Watch Lactase Deficiency [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-lactase-deficiency?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/intestinal-pathology?index=3]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 225: _____ is a powerful diagnostic tool used to amplify a desired fragment of DNA
Answer: Polymerase Chain Reaction (PCR)
Extra:
Watch Recombinant DNA (Overview) Molecular Cloning & PCR [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-recombinant-dna-and-biotechnology-recombinant-dna-overview-molecular-cloning-and-polymerase-chain-reaction?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/laboratory-techniques?index=2]
https://onlinemeded.org?ref=anki
Flashcard 226: Pseudohypoparathyroidism type 1a occurs due to an inherited defect from the _____ due to imprinting
Answer: mother
Extra:
Watch Calcium Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-volume-electrolyte-and-acidbase-disorders-calcium-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/renal?ref=anki
Flashcard 227: The G6PD isoform genes are located on the _____
Answer: X-chromosome
Extra:
https://onlinemeded.org?ref=anki
Flashcard 228: What form of chromatin do Barr bodies exist as?
_____
Answer: Heterochromatin
Extra:
Watch Chromatin Structure [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-chromatin-structure?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=12]
https://onlinemeded.org?ref=anki
Flashcard 229: Lac Operon: In the presence of _____, the repressor protein is unbound from the operator site, leading to increased transcription
Answer: high lactose
Extra:
Watch Lac Operon [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-lac-operon?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=12]
https://onlinemeded.org?ref=anki
Flashcard 230: Patients with kallmann syndrome most commonly have mutations in the _____ or FGFR-1 genes
Answer: KAL-1
Extra:
Watch Amenorrhea [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-reproductive-hormones-and-ovarian-disorders-amenorrhea?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrinology?ref=anki
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