Molecular Genetics — Flashcards

Flashcard 201: Do mitochondrial DNA utilize histones? _____

Answer: No

Flashcard 202: What class of histone is found outside the nucleosome and functions to condense the nucleosome together? _____

Answer: H1

Flashcard 203: Cyclin D1 sits on chromosome _____

Answer: 11

Flashcard 204: What class of diseases is Huntington disease a part of? _____

Answer: Trinucleotide repeat expansion diseases

Flashcard 205: A(n) _____ is the specific location of a gene on a chromosome

Answer: locus

Flashcard 206: In the second step of PCR, DNA primers _____ to specific sequences on each DNA strand to be amplified

Answer: anneal

Flashcard 207: Down syndrome presents with _____ free α-fetoprotein (AFP)

Answer: decreased

Extra: Atlas:

Flashcard 208: Is DNA synthesis high or low fidelity? _____

Answer: High

Flashcard 209: Primary hemochromatosis is due to mutations in the _____ gene on chromosome 6, leading to increased expression of DMT1 and decreased synthesis of Hepcidin

Answer: HFE

Extra: Atlas:

Flashcard 210: Histones are _____ charged because they have a large quantity of lysine and arginine amino acids

Answer: positively