Molecular Genetics — Flashcards

Flashcard 101: _____ is the highest order of packaging of the chromosome

Answer: Heterochromatin

Flashcard 102: Generally, the 5' end of DNA or RNA is a(n) _____ group

Answer: phosphate

Flashcard 103: Does a Dot (slot) blot require gel electrophoresis before analysis? _____

Answer: No!

Flashcard 104: In the first step of PCR, DNA is _____ by using heat to separate the strands

Answer: denatured

Flashcard 105: How many primers are needed for polymerase chain reaction (PCR)? _____

Answer: Two (one for the 3' end of each DNA strand)

Flashcard 106: Hereditary spherocytosis is most often inherited in a(n) _____ pattern

Answer: autosomal dominant

Extra: dominoes, think of structural = AD

Flashcard 107: A(n) _____ occurs when the long arms of 2 acrocentric chromosomes fuse at the centromere and the 2 short arms are lost

Answer: Robertsonian translocation

Flashcard 108: What is the mechanism that results in malignancy from the N-MYC oncogene? _____

Answer: amplification

Flashcard 109: What is the nucleoSide that is made with guanine? _____

Answer: Guanosine

Flashcard 110: What type of collagen makes up blood vessels, uterus, and fetal tissue? _____

Answer: Type III