Metabolism — Flashcards

Flashcard 571: Vitamin C deficiency is characterized by a(n) _____ PT and normal PTT

Answer: normal

Extra: Bleeding in scurvy is characterized by petechiae, ecchymoses, and gingival bleeding. Because the defect is structural (collagen hydroxylation) rather than enzymatic (clotting factors), laboratory coagulation studies (PT/PTT) remain normal.

Flashcard 572: Hemoglobin is made of _____ and _____

Answer: heme

Extra: Other:

Flashcard 573: _____ is a malnutrition disorder that results from a(n) protein-deficient diet

Answer: Kwashiorkor

Flashcard 574: Carbon monoxide may inhibit the ETC by binding _____, preventing transfer of electrons to O2 in complex IV

Answer: Fe2+

Flashcard 575: Conversion of glucose-6-phosphate to 6-phosphogluconate, via G6PD, produces a molecule of _____

Answer: NADPH

Flashcard 576: Dopamine in the CNS may be degraded to 3-methoxytyramine (3-MT) via the enzyme _____

Answer: catechol-O-methyltransferase (COMT)

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 577: 11-deoxycortisol may be converted to _____ via the enzyme 11β-hydroxylase

Answer: cortisol

Flashcard 578: What effect does 11-hydroxylase deficiency have on serum levels of cortisol? _____

Answer: Decreased

Flashcard 579: HGPRT deficiency (Lesch-Nyhan syndrome) results in _____ production of uric acid

Answer: increased

Flashcard 580: Which step of the Krebs cycle directly produces a molecule of GTP? _____

Answer: Succinyl CoA --> Succinate

Extra: Other: