Metabolism US Medical PG Flashcards - Medical Study Cards
Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Metabolism Flashcard Deck - 10 Cards
Flashcard 561: Which **complement protein** level is characteristically **decreased** in **C1 esterase inhibitor deficiency**?
_____
Answer: C4
Extra: C1 esterase inhibitor deficiency leads to unregulated activation of the classical pathway, resulting in excessive consumption of **C4** (and C2).
The lack of kallikrein inhibition leads to increased **bradykinin**, which is the primary mediator of the associated angioedema.
Note: **C3** levels are typically **normal** in this condition, making the generation of C3a/C5a less significant than C4 consumption and bradykinin production.
Flashcard 562: Alcohol dehydrogenase operates via _____-order kinetics
Answer: zero
Extra:
Watch Alcohol Metabolism [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-alcohol-metabolism-alcohol-metabolism?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/psychiatry?ref=anki
PEA: phenytoin, ethanol, and aspirin - same AMOUNT removed per unit time
Flashcard 563: What is the molecular formula for oxidized glutathione?
_____
Answer: Glutathione-sulfur-sulfur-Glutathione (GS-SG)
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 564: The _____ form of hemoglobin is found in most tissues
Answer: taut
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/blood?index=10]
https://onlinemeded.org/spa/heme-onc/hemoglobin/acquire?ref=anki
Flashcard 565: In splenic macrophages, biliverdin is reduced to _____
Answer: (unconjugated) bilirubin
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/physiology?index=10]
https://onlinemeded.org?ref=anki
UWorld:
Flashcard 566: Which amino acid is the precursor to creatine?
_____
Answer: Arginine
Extra:
Watch Amino Acid Derivatives [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-amino-acids-and-proteins-amino-acid-derivatives?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/dna-to-protein/amino-acids/acquire?ref=anki
Flashcard 567: Homocystinuria is a metabolic disorder characterized by excess _____
Answer: homocysteine
Extra:
Watch Homocystinuria [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-amino-acids-and-proteins-homocystinuria?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/coagulation-and-fibrinolysis?index=6]
https://onlinemeded.org/spa/dna-to-protein/amino-acids/acquire?ref=anki
Flashcard 568: 11, 17, and 21 hydroxylase deficiencies are _____
Answer: autosomal recessive
Extra:
Watch Congenital Adrenal Hyperplasia (CAH) [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-adrenal-disorders-congenital-adrenal-hyperplasia-cah?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Congenital Adrenal Hyperplasia (CAH) [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-adrenal-disorders-congenital-adrenal-hyperplasia-cah?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrine?ref=anki
Flashcard 569: The first step in intestinal protein digestion involves activation of _____ (inactive) to _____ (active)
Answer: trypsinogen
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/physiology?index=12]
https://onlinemeded.org?ref=anki
Flashcard 570: Vitamin C deficiency is characterized by a(n) _____ PT and normal PTT
Answer: normal
Extra: Bleeding in scurvy is characterized by petechiae, ecchymoses, and gingival bleeding. Because the defect is structural (collagen hydroxylation) rather than enzymatic (clotting factors), laboratory coagulation studies (PT/PTT) remain normal.
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